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Gene Review

PEX12  -  Peroxisome biogenesis protein 12

Arabidopsis thaliana

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High impact information on APM4/ATPEX12/PEX12


Biological context of APM4/ATPEX12/PEX12

  • Using virus-induced gene-silencing techniques, we demonstrate that peroxisomal number and fluorescence of the yellow fluorescent protein-peroxisome targeting signal type 1 protein are greatly reduced when PEX12 is silenced [2].


  1. The Arabidopsis pex12 and pex13 mutants are defective in both PTS1- and PTS2-dependent protein transport to peroxisomes. Mano, S., Nakamori, C., Nito, K., Kondo, M., Nishimura, M. Plant J. (2006) [Pubmed]
  2. The Arabidopsis PEX12 gene is required for peroxisome biogenesis and is essential for development. Fan, J., Quan, S., Orth, T., Awai, C., Chory, J., Hu, J. Plant Physiol. (2005) [Pubmed]
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