High impact information on RBE

• RBE encodes a SUPERMAN-like protein and is located in the nucleus, and thus may be a transcription factor [1].
• RBE is not expressed in ap1-1 and ptl-1 mutants, indicating that RBE acts downstream of AP1 and PTL genes [1].
• In the development of second-whorl organs, RBE acts in the same pathway and downstream of UNUSUAL FLORAL ORGANS (UFO) [2].
• RBE thus acts to maintain two different types of spatial boundaries in young flowers: boundaries between organ primordia within a whorl and boundaries of homeotic gene expression between whorls [2].
• Both polypeptides contain one conserved serine-stretch and three lysine-rich repeats characteristic of DHN/LEA/RAB-like proteins [3].

Biological context of RBE

• Because of the great variability of the available radiation spectra, the induced relative biological effect (RBE-value) has to be differentiated with respect to the effective charge (z) and the linear energy transfer (LET) deposited in a certain volume of matter, and to the biological targets which differ in size, structure and function [4].
• The significance of the results obtained is discussed with respect to stress and risk and, thus, the quality of the RBE-factors and heavy ionizing radiation all needed for the very definition of radiation protection standards in space [5].

Associations of RBE with chemical compounds

• The gene encodes a hydrophilic, glycine-rich protein (18.5 kDa), which contains the conserved serine- and lysine-rich domains characteristic of similar RAB proteins in other plant species [6].

References