The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

ADK1  -  dual specificity kinase 1

Arabidopsis thaliana

Synonyms: CASEIN KINASE I-LIKE 9 ALPHA, CASEIN KINASE I-LIKE 9 BETA, CKL9ALPHA, CKL9BETA, DUAL SPECIFICITY KINASE 1, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on ADK1

  • Using poly (Glu/Tyr) as a substrate, we confirm that ADK1 is capable of phosphorylating tyrosine residues [1].
  • These results indicate that Ado must be steadily removed by ADK to prevent feedback inhibition of SAH hydrolase and maintain SAM utilization and recycling [2].
  • Adenosine (Ado) kinase (ADK; ATP:Ado 5' phosphotransferase, EC 2.7.1.20) catalyzes the salvage synthesis of adenine monophosphate from Ado and ATP [2].
  • There is a direct correlation between ADK activity and the level of methylesterified pectin in seed mucilage, as monitored by staining with ruthenium red, immunofluorescence labeling, or direct assay [2].
  • Adenosine kinase (ADK, EC 2.7.1.20) is a purine salvage enzyme, which phosphorylates adenosine (Ado) to AMP [3].
 

Anatomical context of ADK1

  • As such, ADK was found to increase during events associated with high transmethylation activity, such as cell wall synthesis and seed filling [3].

References

  1. Cloning and biochemical characterization of a plant protein kinase that phosphorylates serine, threonine, and tyrosine. Ali, N., Halfter, U., Chua, N.H. J. Biol. Chem. (1994) [Pubmed]
  2. Adenosine kinase deficiency is associated with developmental abnormalities and reduced transmethylation. Moffatt, B.A., Stevens, Y.Y., Allen, M.S., Snider, J.D., Pereira, L.A., Todorova, M.I., Summers, P.S., Weretilnyk, E.A., Martin-McCaffrey, L., Wagner, C. Plant Physiol. (2002) [Pubmed]
  3. Applying high throughput techniques in the study of adenosine kinase in plant metabolism and development. Schoor, S., Moffatt, B.A. Front. Biosci. (2004) [Pubmed]
 
WikiGenes - Universities