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Gene Review

Slc34a2  -  solute carrier family 34 (type II...

Rattus norvegicus

Synonyms: Na(+)-dependent phosphate cotransporter 2B, Na(+)/Pi cotransporter 2B, NaPi-2b, Sodium-dependent phosphate transport protein 2B, Sodium-phosphate transport protein 2B, ...
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High impact information on Slc34a2


Analytical, diagnostic and therapeutic context of Slc34a2

  • In situ hybridization showed that rNaPi IIb was expressed in type II alveolar cells, suggesting a role in the synthesis of surfactant in the alveoli [1].
  • Expression of GLUT5 and NaPi2b, the intestinal Na+-dependent phosphate transporter, dramatically increased and decreased, respectively, with HF perfusion for 4 h [3].


  1. Isolation and localization of type IIb Na/Pi cotransporter in the developing rat lung. Hashimoto, M., Wang, D.Y., Kamo, T., Zhu, Y., Tsujiuchi, T., Konishi, Y., Tanaka, M., Sugimura, H. Am. J. Pathol. (2000) [Pubmed]
  2. Nicotinamide prevents the development of hyperphosphataemia by suppressing intestinal sodium-dependent phosphate transporter in rats with adenine-induced renal failure. Eto, N., Miyata, Y., Ohno, H., Yamashita, T. Nephrol. Dial. Transplant. (2005) [Pubmed]
  3. Fructose-responsive genes in the small intestine of neonatal rats. Cui, X.L., Soteropoulos, P., Tolias, P., Ferraris, R.P. Physiol. Genomics (2004) [Pubmed]
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