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FNDC1  -  fibronectin type III domain containing 1

Homo sapiens

Synonyms: AGS8, Activation-associated cDNA protein, Expressed in synovial lining protein, FNDC2, Fibronectin type III domain-containing protein 1, ...
 
 
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Disease relevance of FNDC1

 

High impact information on FNDC1

  • The bioactivity of AGS8 in the yeast-based assay was independent of guanine nucleotide exchange by Galpha, suggesting an impact on subunit interactions [2].
  • MEL4B3, a novel mRNA is induced in skin tumors and regulated by TGF-beta and pro-inflammatory cytokines [1].
  • Here, we report the isolation and characterisation of a novel cDNA (MEL4B3), which is induced in cultured dermal fibroblasts exposed to supernatants of melanoma cell lines [1].
 

Analytical, diagnostic and therapeutic context of FNDC1

References

  1. MEL4B3, a novel mRNA is induced in skin tumors and regulated by TGF-beta and pro-inflammatory cytokines. Anderegg, U., Breitschwerdt, K., Köhler, M.J., Sticherling, M., Haustein, U.F., Simon, J.C., Saalbach, A. Exp. Dermatol. (2005) [Pubmed]
  2. Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. Sato, M., Cismowski, M.J., Toyota, E., Smrcka, A.V., Lucchesi, P.A., Chilian, W.M., Lanier, S.M. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  3. Hepatitis C screenings available at FNDC. Grimaudo, N.J., Lado, E. Today's FDA : official monthly journal of the Florida Dental Association. (2000) [Pubmed]
 
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