Gene Review:
RBM17 - RNA binding motif protein 17
Homo sapiens
Synonyms:
45 kDa-splicing factor, MGC14439, RNA-binding motif protein 17, SPF45, Splicing factor 45
- Splicing regulation at the second catalytic step by Sex-lethal involves 3' splice site recognition by SPF45. Lallena, M.J., Chalmers, K.J., Llamazares, S., Lamond, A.I., Valcárcel, J. Cell (2002)
- Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells. Sampath, J., Long, P.R., Shepard, R.L., Xia, X., Devanarayan, V., Sandusky, G.E., Perry, W.L., Dantzig, A.H., Williamson, M., Rolfe, M., Moore, R.E. Am. J. Pathol. (2003)
- Simplified method to substantiate SPF labeling for sunscreen products. Sayre, R.M., Stanfield, J., Lott, D.L., Dowdy, J.C. Photodermatology, photoimmunology & photomedicine. (2003)
- Sex, AGility, and the regulation of alternative splicing. Graveley, B.R. Cell (2002)
- Human splicing factor SPF45 (RBM17) confers broad multidrug resistance to anticancer drugs when overexpressed--a phenotype partially reversed by selective estrogen receptor modulators. Perry, W.L., Shepard, R.L., Sampath, J., Yaden, B., Chin, W.W., Iversen, P.W., Jin, S., Lesoon, A., O'Brien, K.A., Peek, V.L., Rolfe, M., Shyjan, A., Tighe, M., Williamson, M., Krishnan, V., Moore, R.E., Dantzig, A.H. Cancer Res. (2005)
- A novel DNA repair enzyme containing RNA recognition, G-patch and specific splicing factor 45-like motifs in the protozoan parasite Toxoplasma gondii. Dendouga, N., Callebaut, I., Tomavo, S. Eur. J. Biochem. (2002)
- Structural and functional characterization of the TgDRE multidomain protein, a DNA repair enzyme from Toxoplasma gondii. Frénal, K., Callebaut, I., Wecker, K., Prochnicka-Chalufour, A., Dendouga, N., Zinn-Justin, S., Delepierre, M., Tomavo, S., Wolff, N. Biochemistry (2006)