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Gene Review

POL31  -  Pol31p

Saccharomyces cerevisiae S288c

Synonyms: DNA polymerase delta small subunit, HUS2, HYS2, Hydroxyurea-sensitive protein 2, J1427, ...
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Disease relevance of HYS2


High impact information on HYS2


Biological context of HYS2


Physical interactions of HYS2


Other interactions of HYS2

  • Moreover, regions I and VII of Pol31, which are specifically sensitive to high levels of Mgs1 and PCNA, could be sites of interaction [5].


  1. Characterization of the two small subunits of Saccharomyces cerevisiae DNA polymerase delta. Gerik, K.J., Li, X., Pautz, A., Burgers, P.M. J. Biol. Chem. (1998) [Pubmed]
  2. Structure of DNA polymerase delta from Saccharomyces cerevisiae. Johansson, E., Majka, J., Burgers, P.M. J. Biol. Chem. (2001) [Pubmed]
  3. The second subunit of DNA polymerase III (delta) is encoded by the HYS2 gene in Saccharomyces cerevisiae. Hashimoto, K., Nakashima, N., Ohara, T., Maki, S., Sugino, A. Nucleic Acids Res. (1998) [Pubmed]
  4. HYS2, an essential gene required for DNA replication in Saccharomyces cerevisiae. Sugimoto, K., Sakamoto, Y., Takahashi, O., Matsumoto, K. Nucleic Acids Res. (1995) [Pubmed]
  5. Mgs1 and Rad18/Rad5/Mms2 are required for survival of Saccharomyces cerevisiae mutants with novel temperature/cold sensitive alleles of the DNA polymerase delta subunit, Pol31. Vijeh Motlagh, N.D., Seki, M., Branzei, D., Enomoto, T. DNA Repair (Amst.) (2006) [Pubmed]
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