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Gene Review

ITR2  -  myo-inositol transporter ITR2

Saccharomyces cerevisiae S288c

Synonyms: HRB612, Myo-inositol transporter 2, YOL103W
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High impact information on ITR2


Biological context of ITR2

  • The ITR1 and ITR2 genes contained long open reading frames capable of encoding 584 and 612 amino acids with calculated relative molecular masses of 63,605 and 67,041, respectively [1].

Anatomical context of ITR2


Other interactions of ITR2

  • Itr1p and Itr2p are high and low affinity transporters, respectively [5].

Analytical, diagnostic and therapeutic context of ITR2


  1. Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae. Nikawa, J., Tsukagoshi, Y., Yamashita, S. J. Biol. Chem. (1991) [Pubmed]
  2. Differential regulation of two myo-inositol transporter genes of Saccharomyces cerevisiae. Nikawa, J., Hosaka, K., Yamashita, S. Mol. Microbiol. (1993) [Pubmed]
  3. GIT1, a gene encoding a novel transporter for glycerophosphoinositol in Saccharomyces cerevisiae. Patton-Vogt, J.L., Henry, S.A. Genetics (1998) [Pubmed]
  4. Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Shizosaccharomyces pombe. Niederberger, C., Gräub, R., Schweingruber, A.M., Fankhauser, H., Rusu, M., Poitelea, M., Edenharter, L., Schweingruber, M.E. Curr. Genet. (1998) [Pubmed]
  5. Mutational analysis and localization of the inositol transporters of Saccharomyces cerevisiae. Miyashita, M., Shugyo, M., Nikawa, J. J. Biosci. Bioeng. (2003) [Pubmed]
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