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Gene Review

DAL3  -  ureidoglycolate hydrolase

Saccharomyces cerevisiae S288c

Synonyms: Degradation of allantoin protein 3, Ureidoglycolatase, Ureidoglycolate hydrolase, Ureidoglycolate lyase, YIR032C
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High impact information on DAL3


Biological context of DAL3

  • Here we show that DAL80 protein binds to DAL3 and UGA4 upstream DNA sequences, designated URSGATA, consisting of two GATAA-containing sites separated by at least 15 bp [6].
  • The four carboxy-terminal amino acids of DAL3 product (Cys-Ile-Ile-Ile) are homologous to those (CAAX) previously shown to be the primary structural signal for post-translational farnesylation of yeast RAS protein and mating factor [5].
  • The upstream region of DAL3 contains six copies of a sequence that is homologous to the positively acting DAL UASNTR reported to be required for transcriptional activation of the DAL5 and DAL7 genes [5].


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