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Gene Review

NTE1  -  Nte1p

Saccharomyces cerevisiae S288c

Synonyms: Intracellular phospholipase B, Lysophospholipase NTE1, Neuropathy target esterase homolog, YM9958.03C, YML059C
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High impact information on NTE1


Biological context of NTE1

  • Consistent with a role in lipid and membrane homeostasis, Nte1p-mediated PtdCho deacylation is strongly affected by Sec14p, a component of the yeast secretory machinery characterized by its ability to interface between lipid metabolism and vesicular trafficking [3].

Associations of NTE1 with chemical compounds

  • We monitored Nte1p activity through in vivo PC turnover measurements and observed that intracellular GPCho accumulation is decreased in a sec14(ts) strain shifted to 37 degrees C in 10 mm choline (Cho)-containing medium compared with a Sec14p-proficient strain [1].


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