Gene Review:
SEC14 - phosphatidylinositol/phosphatidylcholine...
Saccharomyces cerevisiae S288c
Synonyms:
PI/PC TP, PIT1, Phosphatidylinositol/phosphatidylcholine transfer protein, SEC14 cytosolic factor, YM9582.04, ...
- Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. Fang, M., Kearns, B.G., Gedvilaite, A., Kagiwada, S., Kearns, M., Fung, M.K., Bankaitis, V.A. EMBO J. (1996)
- Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein. Cleves, A.E., McGee, T.P., Whitters, E.A., Champion, K.M., Aitken, J.R., Dowhan, W., Goebl, M., Bankaitis, V.A. Cell (1991)
- Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein. Sha, B., Phillips, S.E., Bankaitis, V.A., Luo, M. Nature (1998)
- Essential role for diacylglycerol in protein transport from the yeast Golgi complex. Kearns, B.G., McGee, T.P., Mayinger, P., Gedvilaite, A., Phillips, S.E., Kagiwada, S., Bankaitis, V.A. Nature (1997)
- Evidence for an intrinsic toxicity of phosphatidylcholine to Sec14p-dependent protein transport from the yeast Golgi complex. Xie, Z., Fang, M., Bankaitis, V.A. Mol. Biol. Cell (2001)
- The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex. Bankaitis, V.A., Malehorn, D.E., Emr, S.D., Greene, R. J. Cell Biol. (1989)
- Phosphatidylcholine synthesis influences the diacylglycerol homeostasis required for SEC14p-dependent Golgi function and cell growth. Henneberry, A.L., Lagace, T.A., Ridgway, N.D., McMaster, C.R. Mol. Biol. Cell (2001)
- Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3' untranslated region. Chinen, K., Takahashi, E., Nakamura, Y. Cytogenet. Cell Genet. (1996)
- Phospholipid transfer activity is relevant to but not sufficient for the essential function of the yeast SEC14 gene product. Skinner, H.B., Alb, J.G., Whitters, E.A., Helmkamp, G.M., Bankaitis, V.A. EMBO J. (1993)
- Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. Hama, H., Schnieders, E.A., Thorner, J., Takemoto, J.Y., DeWald, D.B. J. Biol. Chem. (1999)
- Isolation of a cDNA from Arabidopsis thaliana that complements the sec14 mutant of yeast. Jouannic, N., Lepetit, M., Vergnolle, C., Cantrel, C., Gardies, A.M., Kader, J.C., Arondel, V. Eur. J. Biochem. (1998)
- An essential role for a phospholipid transfer protein in yeast Golgi function. Bankaitis, V.A., Aitken, J.R., Cleves, A.E., Dowhan, W. Nature (1990)
- Role of the yeast phosphatidylinositol/phosphatidylcholine transfer protein (Sec14p) in phosphatidylcholine turnover and INO1 regulation. Patton-Vogt, J.L., Griac, P., Sreenivas, A., Bruno, V., Dowd, S., Swede, M.J., Henry, S.A. J. Biol. Chem. (1997)
- Regulation of phospholipid biosynthesis by phosphatidylinositol transfer protein Sec14p and its homologues. A critical role for phosphatidic acid. Holic, R., Zágorsek, M., Griac, P. Eur. J. Biochem. (2004)
- Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Xie, Z., Fang, M., Rivas, M.P., Faulkner, A.J., Sternweis, P.C., Engebrecht, J.A., Bankaitis, V.A. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. Rivas, M.P., Kearns, B.G., Xie, Z., Guo, S., Sekar, M.C., Hosaka, K., Kagiwada, S., York, J.D., Bankaitis, V.A. Mol. Biol. Cell (1999)
- Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily. Schaaf, G., Ortlund, E.A., Tyeryar, K.R., Mousley, C.J., Ile, K.E., Garrett, T.A., Ren, J., Woolls, M.J., Raetz, C.R., Redinbo, M.R., Bankaitis, V.A. Mol. Cell (2008)
- Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth. Li, X., Routt, S.M., Xie, Z., Cui, X., Fang, M., Kearns, M.A., Bard, M., Kirsch, D.R., Bankaitis, V.A. Mol. Biol. Cell (2000)
- A new gene involved in the transport-dependent metabolism of phosphatidylserine, PSTB2/PDR17, shares sequence similarity with the gene encoding the phosphatidylinositol/phosphatidylcholine transfer protein, SEC14. Wu, W.I., Routt, S., Bankaitis, V.A., Voelker, D.R. J. Biol. Chem. (2000)
- SUT1 suppresses sec14-1 through upregulation of CSR1 in Saccharomyces cerevisiae. Régnacq, M., Ferreira, T., Puard, J., Bergès, T. FEMS Microbiol. Lett. (2002)
- Two transcripts, differing at their 3' ends, are produced from the Candida albicans SEC14 gene. Riggle, P.J., Slobodkin, I.V., Brown, D.H., Hanson, M.P., Volkert, T.L., Kumamoto, C.A. Microbiology (Reading, Engl.) (1997)
- Cloning of Candida albicans SEC14 gene homologue coding for a putative essential function. Monteoliva, L., Sánchez, M., Pla, J., Gil, C., Nombela, C. Yeast (1996)
- Transformations of membrane-bound organelles in sec 14 mutants of the yeasts Saccharomyces cerevisiae and Yarrowia lipolytica. Rambourg, A., Clermont, Y., Nicaud, J.M., Gaillardin, C., Kepes, F. Anat. Rec. (1996)
- Crystallization and preliminary X-ray diffraction analysis of phospholipid-bound Sfh1p, a member of the Saccharomyces cerevisiae Sec14p-like phosphatidylinositol transfer protein family. Schaaf, G., Betts, L., Garrett, T.A., Raetz, C.R., Bankaitis, V.A. Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. (2006)