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SKS1  -  Sks1p

Saccharomyces cerevisiae S288c

Synonyms: LPB5, SHA3, Serine/threonine-protein kinase SKS1, Suppressor kinase of SNF3, YPL026C
 
 
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High impact information on SKS1

  • This conclusion was corroborated by finding an inverse relationship of the CBC1 and SKS1 mRNA levels in normal strains grown under different conditions [1].
  • Under certain growth conditions, over-expression of SKS1 itself leads to a growth defect which is diminished in snf3 hxt2 double mutants [2].
  • SKS1 defines a novel, Snf3p-independent pathway for the expression of Hxt2p [2].
  • The SKS1 gene of Saccharomyces cerevisiae is required for long-term adaptation of snf3 null strains to low glucose [2].
  • Overexpression of the SKS1 open reading frame is sufficient for suppression of the growth defects of snf3 mutants [3].
 

Biological context of SKS1

  • A DDSE (DNA dependent snf3 suppressor element) was found to be present in the SKS1 promoter region [3].
  • A multicopy suppressor of the snf3 growth defect, SKS1 (suppressor kinase of snf3), was found to encode a putative ser/thr protein kinase homologous to Ran1p, a kinase that regulates the switch between meiosis and vegetative growth in Schizosaccharomyces pombe [3].
 

Associations of SKS1 with chemical compounds

  • Both SKS1 and its DDSE can additionally suppress the growth defects of grr1 mutants, which are also impaired in high affinity glucose transport [3].
 

Other interactions of SKS1

References

 
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