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Gene Review

NPR2  -  Npr2p

Saccharomyces cerevisiae S288c

Synonyms: Nitrogen permease regulator 2, YEL062W
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Disease relevance of NPR2


High impact information on NPR2


Associations of NPR2 with chemical compounds

  • Therefore, we generated yeast npr2Delta sky1Delta double-knockout cells and performed clonogenic survival assays for cisplatin and doxorubicin, which revealed that NPR2 and SKY1 (SR-protein-specific kinase from budding yeast) are epistatic [1].


  1. Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill. Schenk, P.W., Brok, M., Boersma, A.W., Brandsma, J.A., Den Dulk, H., Burger, H., Stoter, G., Brouwer, J., Nooter, K. Mol. Pharmacol. (2003) [Pubmed]
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