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Gene Review:

polA - DNA polymerase I

Pseudomonas aeruginosa PAO1

Lehrbach, P.R. et al., Sanders, L.H. et al.

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Disease relevance of polA

R plasmids pMG1, R2, R931 and pMG15 increased the survival of Pseudomonas aeruginosa exposed to ultraviolet radiation (u.v.) in the wild type, and uvr and polA mutants but did not alter the u.v.-response of a recA mutant [1].

High impact information on polA

Possible roles of the P. aeruginosa dinB, polA, and polC gene products in mutagenesis are discussed [2].
The R plasmid RPL11 reduced u.v.-survival in the wild type, and uvr and polA mutants but did not alter the u.v.-response of a recA host [1].

References

R plasmids which alter ultraviolet light-sensitivity and enhance ultraviolet light-induced mutability in Pseudomonas aeruginosa. Lehrbach, P.R., Kung, A.H., Lee, B.T. J. Gen. Microbiol. (1978) [Pubmed]
Role of Pseudomonas aeruginosa dinB-Encoded DNA Polymerase IV in Mutagenesis. Sanders, L.H., Rockel, A., Lu, H., Wozniak, D.J., Sutton, M.D. J. Bacteriol. (2006) [Pubmed]

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