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Gene Review

mecA  -  adaptor protein

Streptococcus pneumoniae R6

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Disease relevance of mecA


High impact information on mecA

  • The result of the mecA gene detection module correlated with the result of the phenotypic oxacillin resistance testing in all 38 isolates of Staphylococcus aureus investigated [3].
  • The three discrepant MRSA strains displayed positive results only after induction of the mecA gene by exposure to methicillin [2].


  1. Resistant penicillin-binding proteins. Hakenbeck, R., Coyette, J. Cell. Mol. Life Sci. (1998) [Pubmed]
  2. Rapid detection of methicillin resistance in Staphylococcus aureus isolates by the MRSA-screen latex agglutination test. van Leeuwen, W.B., van Pelt, C., Luijendijk, A., Verbrugh, H.A., Goessens, W.H. J. Clin. Microbiol. (1999) [Pubmed]
  3. Evaluation of the Hyplex BloodScreen Multiplex PCR-Enzyme-linked immunosorbent assay system for direct identification of gram-positive cocci and gram-negative bacilli from positive blood cultures. Wellinghausen, N., Wirths, B., Essig, A., Wassill, L. J. Clin. Microbiol. (2004) [Pubmed]
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