The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Enterobacter


High impact information on Enterobacter


Chemical compound and disease context of Enterobacter


Biological context of Enterobacter


Anatomical context of Enterobacter


Gene context of Enterobacter

  • In clinical isolates of Enterobacter cloacae, resistance to the newer beta-lactam antibiotics often results from overproduction of a cephalosporinase encoded by the beta-lactam-inducible ampC gene [26].
  • ampG is essential for high-level expression of AmpC beta-lactamase in Enterobacter cloacae [27].
  • A recombinant fusion protein, L49-sFv-bL, that contains the antibody binding regions of L49 fused to the Enterobacter cloacae r2-1 beta-lactamase (bL) was constructed, expressed, and purified to homogeneity in an Escherichia coli soluble expression system [28].
  • To study the function of the OmpX protein and its role in the regulation of porin protein synthesis, the ompX gene was deleted from the Enterobacter cloacae chromosome and replaced by the aphA gene [29].
  • Detection of mutations in the gyrA and parC genes in quinolone-resistant clinical isolates of Enterobacter cloacae [30].

Analytical, diagnostic and therapeutic context of Enterobacter


  1. Inducible cephalosporinase production in clinical isolates of Enterobacter cloacae is controlled by a regulatory gene that has been deleted from Escherichia coli. Honoré, N., Nicolas, M.H., Cole, S.T. EMBO J. (1986) [Pubmed]
  2. Trimethoprim-sulfamethoxazole for bacterial meningitis. Levitz, R.E., Quintiliani, R. Ann. Intern. Med. (1984) [Pubmed]
  3. Pyridoxal phosphate-dependent histidine decarboxylases. Cloning, sequencing, and expression of genes from Klebsiella planticola and Enterobacter aerogenes and properties of the overexpressed enzymes. Kamath, A.V., Vaaler, G.L., Snell, E.E. J. Biol. Chem. (1991) [Pubmed]
  4. Detergent-shock response in enteric bacteria. Nickerson, K.W., Aspedon, A. Mol. Microbiol. (1992) [Pubmed]
  5. Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria. Holden, M.T., Ram Chhabra, S., de Nys, R., Stead, P., Bainton, N.J., Hill, P.J., Manefield, M., Kumar, N., Labatte, M., England, D., Rice, S., Givskov, M., Salmond, G.P., Stewart, G.S., Bycroft, B.W., Kjelleberg, S., Williams, P. Mol. Microbiol. (1999) [Pubmed]
  6. Inhibition of a class C beta-lactamase by a specific phosphonate monoester. Pratt, R.F. Science (1989) [Pubmed]
  7. Enterobacter resistant to amoxycillin/clavulanate. Crump, J., Cansdale, S. Lancet (1982) [Pubmed]
  8. Analysis of a carbapenem-hydrolyzing class A beta-lactamase from Enterobacter cloacae and of its LysR-type regulatory protein. Naas, T., Nordmann, P. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  9. Regressions and cures of melanoma xenografts following treatment with monoclonal antibody beta-lactamase conjugates in combination with anticancer prodrugs. Kerr, D.E., Schreiber, G.J., Vrudhula, V.M., Svensson, H.P., Hellström, I., Hellström, K.E., Senter, P.D. Cancer Res. (1995) [Pubmed]
  10. Atomic resolution structures and solution behavior of enzyme-substrate complexes of Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase. Multiple conformational states and implications for the mechanism of nitroaromatic explosive degradation. Khan, H., Barna, T., Harris, R.J., Bruce, N.C., Barsukov, I., Munro, A.W., Moody, P.C., Scrutton, N.S. J. Biol. Chem. (2004) [Pubmed]
  11. Purification and characterization of indolepyruvate decarboxylase. A novel enzyme for indole-3-acetic acid biosynthesis in Enterobacter cloacae. Koga, J., Adachi, T., Hidaka, H. J. Biol. Chem. (1992) [Pubmed]
  12. Purification and characterization of PrbA, a new esterase from Enterobacter cloacae hydrolyzing the esters of 4-hydroxybenzoic acid (parabens). Valkova, N., Lépine, F., Labrie, L., Dupont, M., Beaudet, R. J. Biol. Chem. (2003) [Pubmed]
  13. Purification and characterization of an oxygen-insensitive NAD(P)H nitroreductase from Enterobacter cloacae. Bryant, C., DeLuca, M. J. Biol. Chem. (1991) [Pubmed]
  14. 5-Methylthioribose kinase. A new enzyme involved in the formation of methionine from 5-methylthioribose. Ferro, A.J., Barrett, A., Shapiro, S.K. J. Biol. Chem. (1978) [Pubmed]
  15. Structures of nitroreductase in three states: effects of inhibitor binding and reduction. Haynes, C.A., Koder, R.L., Miller, A.F., Rodgers, D.W. J. Biol. Chem. (2002) [Pubmed]
  16. Chemical complementation: a reaction-independent genetic assay for enzyme catalysis. Baker, K., Bleczinski, C., Lin, H., Salazar-Jimenez, G., Sengupta, D., Krane, S., Cornish, V.W. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  17. New beta -lactamase inhibitory protein (BLIP-I) from Streptomyces exfoliatus SMF19 and its roles on the morphological differentiation. Kang, S.G., Park, H.U., Lee, H.S., Kim, H.T., Lee, K.J. J. Biol. Chem. (2000) [Pubmed]
  18. Structural basis for the extended substrate spectrum of CMY-10, a plasmid-encoded class C beta-lactamase. Kim, J.Y., Jung, H.I., An, Y.J., Lee, J.H., Kim, S.J., Jeong, S.H., Lee, K.J., Suh, P.G., Lee, H.S., Lee, S.H., Cha, S.S. Mol. Microbiol. (2006) [Pubmed]
  19. A multidrug resistance regulatory chromosomal locus is widespread among enteric bacteria. Cohen, S.P., Yan, W., Levy, S.B. J. Infect. Dis. (1993) [Pubmed]
  20. mar Operon involved in multidrug resistance of Enterobacter aerogenes. Chollet, R., Bollet, C., Chevalier, J., Malléa, M., Pagès, J.M., Davin-Regli, A. Antimicrob. Agents Chemother. (2002) [Pubmed]
  21. Antibacterial activity and beta-lactamase stability of temocillin. Jules, K., Neu, H.C. Antimicrob. Agents Chemother. (1982) [Pubmed]
  22. C-reactive protein, ESR, and klebsiella in ankylosing spondylitis. Cowling, P., Ebringer, R., Cawdell, D., Ishii, M., Ebringer, A. Ann. Rheum. Dis. (1980) [Pubmed]
  23. A double-blind comparison of the effects of cefaclor and amoxycillin on respiratory tract and oropharyngeal flora and clinical response in acute exacerbations of bronchitis. Trigg, C.J., Wilks, M., Herdman, M.J., Clague, J.E., Tabaqchali, S., Davies, R.J. Respiratory medicine. (1991) [Pubmed]
  24. Decolorization of azo dyes with Enterobacter agglomerans immobilized in different supports by using fluidized bed bioreactor. Moutaouakkil, A., Zeroual, Y., Dzayri, F.Z., Talbi, M., Lee, K., Blaghen, M. Curr. Microbiol. (2004) [Pubmed]
  25. Chemotactic activity of chicken blood mononuclear leukocytes from 15I5-B-congenic lines to bacterially-derived chemoattractants. Qureshi, M.A., Dietert, R.R., Bacon, L.D. Vet. Immunol. Immunopathol. (1988) [Pubmed]
  26. Regulation of enterobacterial cephalosporinase production: the role of a membrane-bound sensory transducer. Honoré, N., Nicolas, M.H., Cole, S.T. Mol. Microbiol. (1989) [Pubmed]
  27. ampG is essential for high-level expression of AmpC beta-lactamase in Enterobacter cloacae. Korfmann, G., Sanders, C.C. Antimicrob. Agents Chemother. (1989) [Pubmed]
  28. Construction, expression, and activities of L49-sFv-beta-lactamase, a single-chain antibody fusion protein for anticancer prodrug activation. Siemers, N.O., Kerr, D.E., Yarnold, S., Stebbins, M.R., Vrudhula, V.M., Hellström, I., Hellström, K.E., Senter, P.D. Bioconjug. Chem. (1997) [Pubmed]
  29. Biological characterization of an Enterobacter cloacae outer membrane protein (OmpX). Stoorvogel, J., van Bussel, M.J., van de Klundert, J.A. J. Bacteriol. (1991) [Pubmed]
  30. Detection of mutations in the gyrA and parC genes in quinolone-resistant clinical isolates of Enterobacter cloacae. Deguchi, T., Yasuda, M., Nakano, M., Ozeki, S., Kanematsu, E., Nishino, Y., Ishihara, S., Kawada, Y. J. Antimicrob. Chemother. (1997) [Pubmed]
  31. Cefmenoxime therapy in bacterial osteomyelitis. Sheftel, T.G., Cierny, G., Lefrock, J.L., Mader, J.T. Am. J. Med. (1984) [Pubmed]
  32. Fluoroquinolones protective against cephalosporin resistance in gram-negative nosocomial pathogens. Schwaber, M.J., Cosgrove, S.E., Gold, H.S., Kaye, K.S., Carmeli, Y. Emerging Infect. Dis. (2004) [Pubmed]
  33. A dramatic change in the rate-limiting step of beta-lactam hydrolysis results from the substitution of the active-site serine residue by a cysteine in the class-C beta-lactamase of Enterobacter cloacae 908R. Dubus, A., Monnaie, D., Jacobs, C., Normark, S., Frère, J.M. Biochem. J. (1993) [Pubmed]
  34. Molecular epidemiology of an outbreak of multidrug-resistant Enterobacter aerogenes infections and in vivo emergence of imipenem resistance. De Gheldre, Y., Maes, N., Rost, F., De Ryck, R., Clevenbergh, P., Vincent, J.L., Struelens, M.J. J. Clin. Microbiol. (1997) [Pubmed]
  35. The UDP-N-acetylglucosamine 1-carboxyvinyl-transferase of Enterobacter cloacae. Molecular cloning, sequencing of the gene and overexpression of the enzyme. Wanke, C., Falchetto, R., Amrhein, N. FEBS Lett. (1992) [Pubmed]
WikiGenes - Universities