Disease relevance of Phycodnaviridae

• Ultraviolet (UV) sensitivity and photoreactivation of blue-green algae Cylindrospermum sp., Plectonema boryanum, spores of Fischerella muscicola and algal virus (cyanophage) LPP-1 were studied [1].
• The Phycodnaviridae, Iridoviridae and related viruses, with diameters of 1500-2000 A, are formed from large trigonal arrays of hexagonally close-packed capsomers forming the faces of icosahedra [Yan et al. (2000), Nature Struct. Biol. 7, 101-103; Nandhagopal et al. (2002), Proc. Natl Acad. Sci. USA, 99, 14758-14763] [2].
• The stability of the blue-green algal virus N-1, infecting the blue-green alga Nostoc muscorum, against temperature, EDTA and pH was studied [3].

High impact information on Phycodnaviridae

• Furthermore, the presence of six RNA polymerase subunits (unique among the Phycodnaviridae) suggests both a unique evolutionary history and a unique lifestyle for this intriguing virus [4].
• The Ectocarpus siliculosus Virus-1, EsV-1, is the type-species of a genus of Phycodnaviridae, the phaeoviruses, infecting marine filamentous brown algae [5].
• The brown algal virus EsV-1 particle contains a putative hybrid histidine kinase [6].
• An upstream region isolated from a eukaryotic algal virus adenine methyltransferase gene was tested for promoter function in plants [7].

Chemical compound and disease context of Phycodnaviridae

• Ultraviolet light (UV) sensitivity and photoreactivation of algal virus (cyanophage) LPP-1 were studied after multiplication in host alga Plectonema boryanum in presence of 5-bromouracil (5-BU) alone and in conjunction with sulfanilamide [8].

Biological context of Phycodnaviridae

• Genetic diversity in marine algal virus communities as revealed by sequence analysis of DNA polymerase genes [9].

Gene context of Phycodnaviridae

• Characterization and immunolocalization of major structural proteins in the brown algal virus EsV-1 [10].

References