Disease relevance of Algae, Brown

• The tests on brown algae found that as compared with ammonium, the toxicity to nitrate-grown cultures is higher by a factor of about 10 [1].
• As a part of a screening program for natural products from microorganisms, 465 actinomycetes strains and 278 fungal strains were isolated from 44 seaweed specimens (Rhodophyta and Phaeophyta), collected in the Iberian peninsula seashore (Atlantic and Mediterranean coasts) [2].

High impact information on Algae, Brown

• A p34 protein is detectable in oats and Arabidopsis and in remote taxa, including red and brown algae [3].
• Higher plants produce the C11 hydrocarbons from dodeca-3,6,9-trienoic acid; brown algae exploit the family of icosanoids for biosynthesis of the same compounds [4].
• Thus, the branched fucans from brown algae are direct inhibitors of thrombin, whereas the linear fucans from echinoderms require the presence of antithrombin or heparin cofactor II for inhibition of thrombin, as reported for mammalian glycosaminoglycans [5].
• Dictyoxepin and dictyolene, two new diterpenes from the marine alga Dictyota acutiloba (Phaeophyta) [6].
• These studies of the brown algae Fucus distichus examined whether auxin and auxin transport are also required during polarization in early embryos and to orient growth in already developed tissues [7].

Biological context of Algae, Brown

• Phylogeny of Alariaceae, Laminariaceae, and Lessoniaceae (Phaeophyceae) based on plastid-encoded RuBisCo spacer and nuclear-encoded ITS sequence comparisons [8].
• Distributions and seasonal variations of the key seafood flavor compounds including 2-bromophenol, 4-bromophenol, 2,4-dibromophenol, 2,6-dibromophenol, and 2,4,6-tribromophenol in three species of brown algae (Padina arborescens, Sargassum siliquastrum, and Lobophora variegata) found in Hong Kong waters were investigated [9].
• Agardh (Phaeophyta) were screened for their protective effects against acetaminophen (ACP; Paracetamol)-induced lipid peroxidation in rats [10].
• An in vitro study of the structure-activity relationships of sulfated polysaccharide from brown algae to its antioxidant effect [11].

Anatomical context of Algae, Brown

• Exceptions to this are a heparan sulfate from bovine pancreas and a sulfated fucan derived from brown algae, which have no hemorrhagic activity but have high antithrombotic activities "in vivo". Once the structure of these compounds are totally defined it will be possible to design an ideal antithrombotic [12].
• Several cyclic and alicyclic C11 hydrocarbons have been shown to act as gamete releasing and/or attracting pheromones during sexual reproduction of brown algae (Phaeophyceae) [13].
• In the present communication, we found that fucosterol, which is present mainly in brown algae, Phaeophyta, enhances the production of plasminogen activator in endothelial cells, as well as sitosterol [14].
• Thylakoid membranes from several brown algae have been fragmented with the non-ionic detergent, Triton X-100 [15].

Associations of Algae, Brown with chemical compounds

• Alginate is an industrially important polysaccharide obtained commercially by harvesting brown algae [16].
• The subunit fold and dimer organisation of the Cor. officinalis vanadium bromoperoxidase are similar to those of the dimeric enzyme from the brown algae Ascophyllum nodosum, with which it shares 33 % sequence identity [17].
• Brown algae fucoxanthin is hydrolyzed to fucoxanthinol during absorption by Caco-2 human intestinal cells and mice [18].
• The metabolic fate in mammals of dietary fucoxanthin, a major carotenoid in brown algae, is not known [18].
• Three species of brown algae, Laminaria sinclairii, L. saccharina and L. setchellii, have been investigated for the presence of oxylipins [19].

Gene context of Algae, Brown

• In this paper, we investigated interactions of the acidic oligosaccharide sugar chain (AOSC), derived from brown algae Echlonia kurome OKAM, with amyloid beta protein (Abeta) [20].
• In general, the red algae metabolize C20 acids via 12-lipoxygenase-initiated pathways, green algae metabolize C18 acids at C-9 and C-13, and brown algae metabolize both C18 and C20 acids, principally by lipoxygenases with n-6 specificity [21].

References