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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
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Disease relevance of Duodenostomy

  • For oral tolerization, we administered to the immunized rats protein extracts of a recombinant adenovirus type 5 (1-1.5 mg/day) via duodenostomy tubes 10 to 40 days after the initial virus injection; control rats received bovine serum albumin [1].

High impact information on Duodenostomy

  • In the case of large pancreatic lesions, endoscopic tattoo with dye-India ink or methylene blue may become helpful for the surgeon to perform local resection via duodenostomy [2].
  • Prepubescent rabbits (n = 24) were divided into four groups: CONTROL, fed standard lab chow; TPN, received a standard hyperalimentation solution of dextrose, Aminosyn, and lipids via the jugular vein; ENT, received the same hyperalimentation solution via a duodenostomy tube; and OSM, received a polymeric formula (Osmolite) via a duodenostomy tube [3].
  • Intestino-gastric reflux was measured in dogs with duodenostomy and gastrostomy by using chromium-51 injected through the duodenostomy [4].
  • In one dog, provided with a continent duodenostomy, the radioactivity in duodenal samples was found to vary moderately 24-32 hours after injection of labelled cholic acid [5].


  1. Oral tolerization to adenoviral proteins permits repeated adenovirus-mediated gene therapy in rats with pre-existing immunity to adenoviruses. Ilan, Y., Sauter, B., Chowdhury, N.R., Reddy, B.V., Thummala, N.R., Droguett, G., Davidson, A., Ott, M., Horwitz, M.S., Chowdhury, J.R. Hepatology (1998) [Pubmed]
  2. Endoscopic ultrasonography in patients with gastrinomas. Tio, T.L. Italian journal of gastroenterology and hepatology. (1999) [Pubmed]
  3. Hepatobiliary dysfunction during total parenteral nutrition is caused by infusate, not the route of administration. Moss, R.L., Das, J.B., Ansari, G., Raffensperger, J.G. J. Pediatr. Surg. (1993) [Pubmed]
  4. Intestino-gastric reflux in dogs: spontaneous, after gastrojejunostomy, and after Roux-en-Y gastrojejunostomy with various lengths of the defunctioning loop. Rokkjaer, M., Marqversen, J. Scand. J. Gastroenterol. (1979) [Pubmed]
  5. Determination of duodenogastric reflux by use of 14C-labelled cholic acid. An experimental study in dogs. Svensson, J.O., Jagenburg, R., Kock, N.G. Acta chirurgica Scandinavica. (1980) [Pubmed]
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