High impact information on Research Subjects

• RESULTS: Large proportions of potential research subjects were excluded under most of the criteria tested [1].
• This low radiation burden will allow more than 370 MBq (10 mCi) to be administered to healthy research subjects during each study of the D2 receptor [2].
• Male research subjects were administered placebo and three doses of d-amphetamine (5, 10 and 20 mg/70 kg) in a laboratory situation which provided both aggressive and non-aggressive response options [3].
• The effects of ethanol on cigarette smoking were assessed in volunteer research subjects who had histories of light to moderate social drinking [4].
• In the present study, we combined acute immediate-release (IR) isradipine with repeated sustained-release (SR) isradipine pretreatment to determine whether isradipine could antagonize methamphetamine's positive subjective and reinforcing effects in methamphetamine-dependent research subjects [5].

Biological context of Research Subjects

• Therefore, the elucidation of beta-catenin target genes is a key research subject in understanding the molecular mechanisms of the early embryogenesis of animals [6].

Associations of Research Subjects with chemical compounds

• Additional study with larger numbers of subjects will be helpful in further assessing the safety of administering smoked cocaine to research subjects [7].
• We exposed 14 human research subjects to carbon monoxide until their carboxyhemoglobin levels reached 10% to 12% [8].
• We then treated each research subject with 60 minutes of hyperoxia with or without normocapnia [8].
• BACKGROUND: The efficacy of a new pharmacologic agent for asthma, in this instance the leukotriene receptor antagonist montelukast, is determined in controlled trials in research subjects [9].
• Famotidine treatment of children with autistic spectrum disorders: pilot research using single subject research design [10].

Gene context of Research Subjects

• Human subjects research. Pediatric study of ADHD drug draws high-level public review [11].
• Subjects were 100 patients who had previously sustained moderate-to-severe TBI who were enrolled as research subjects in the UCLA Brain Injury Research Center, and 30 matched control subjects who had sustained traumatic injuries other than to the head six months prior to evaluation [12].
• How to interpret the federal policy for the protection of human subjects or "Common Rule" (Part A). [for the Working Group of the Human Subjects Research Subcommittee of the National Science and Technology Council.] [13].
• Children have been used as research subjects in a diverse set of experiments, including the trials of new vaccines and sera, in efforts to understand normal pediatric anatomy and physiology and in the development of new drugs and procedures [14].
• The majority of the research subjects who scored between 400 and 500 on the TOEFL achieved a grade level of less than 8.0 on the California Achievement Test [15].

Analytical, diagnostic and therapeutic context of Research Subjects

• To assess the representativeness of subjects participating in clinical trials, 243 research subjects participating in clinical trials of treatments for cocaine dependence were compared to a sub-sample of 213 individuals being treated for cocaine dependence in outpatient clinical settings from a large national database [16].

References