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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gelsemium

 
 
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High impact information on Gelsemium

  • Structure reinvestigation of gelsemoxonine, a constituent of Gelsemium elegans, reveals a novel, azetidine-containing indole alkaloid [1].
  • New oxindole alkaloids and iridoid from Carolina jasmine (Gelsemium sempervirens Ait. f.) [2].
  • Three new gelsedine-type oxindole alkaloids, GS-1, GS-2, and GS-3, and one new iridoid, GSIR-1, were isolated from the stems and leaves of cultivated Carolina jasmine (Gelsemium sempervirens AIT. f.) and their structures were determined by spectroscopic analysis [2].
  • A new pregnane derivative, 12 beta-hydroxy-5 alpha-pregn-16-ene-3,20-dione, along with the known derivative 12 beta-hydroxy-pregna-4,16-diene-3,20-dione have been isolated from a MeOH extract of the stem of Gelsemium sempervirens and found to be the principal cytotoxic entities [3].
  • Rankinidine, a new indole alkaloid from Gelsemium rankinii [4].
 

Associations of Gelsemium with chemical compounds

  • 14 beta-Hydroxygelsedine, a new oxindole alkaloid from Gelsemium sempervirens [5].
  • The crude methanol extracts of Gelsemium elegans leaves were assessed for their cytotoxic activity using the microculture 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay for cellular viability [6].
  • Spatial patterns of nitrate, chloride, sulfate, and fluoride concentrations in the Woodbine Aquifer of north-central Texas [7].

References

  1. Structure reinvestigation of gelsemoxonine, a constituent of Gelsemium elegans, reveals a novel, azetidine-containing indole alkaloid. Kitajima, M., Kogure, N., Yamaguchi, K., Takayama, H., Aimi, N. Org. Lett. (2003) [Pubmed]
  2. New oxindole alkaloids and iridoid from Carolina jasmine (Gelsemium sempervirens Ait. f.). Kitajima, M., Urano, A., Kogure, N., Takayama, H., Aimi, N. Chem. Pharm. Bull. (2003) [Pubmed]
  3. Cytotoxic steroids of Gelsemium sempervirens. Schun, Y., Cordell, G.A. J. Nat. Prod. (1987) [Pubmed]
  4. Rankinidine, a new indole alkaloid from Gelsemium rankinii. Schun, Y., Cordell, G.A. J. Nat. Prod. (1986) [Pubmed]
  5. 14 beta-Hydroxygelsedine, a new oxindole alkaloid from Gelsemium sempervirens. Schun, Y., Cordell, G.A. J. Nat. Prod. (1985) [Pubmed]
  6. A Study of the in vitro cytotoxic activity of Gelsemium elegans using human ovarian and breast cancer cell lines. Abdul Wahab, K., Ahmad, F.B., Din, L.B., Swee Hung, C., Shiueh Lian, M. Tropical biomedicine. (2004) [Pubmed]
  7. Spatial patterns of nitrate, chloride, sulfate, and fluoride concentrations in the Woodbine Aquifer of north-central Texas. Hudak, P.F., Sanmanee, S. Environmental monitoring and assessment. (2003) [Pubmed]
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