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MeSH Review

Acanthoma

 
 
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Disease relevance of Acanthoma

 

High impact information on Acanthoma

  • Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency [2].
  • Immunohistochemical characterization of keratin expression in clear cell acanthoma [3].
  • In this study, seven cases of clear cell acanthoma were analysed by immunohistochemical techniques, using various monoclonal antikeratin antibodies, and antibodies against filaggrin, involucrin and epithelial membrane antigen [3].
  • 8. The percentage of cells with positive nuclear staining for PCNA/cyclin was < 20% in all cases of large-cell acanthoma [4].
  • Sections from paraffin-embedded tissues identified histologically as epidermolytic acanthoma were examined for the presence of human papillomavirus (HPV) types 6, 11, 16, 18, and 33 using the polymerase chain reaction followed by dot-blot analysis with specific radiolabelled detecting probes [5].
 

Chemical compound and disease context of Acanthoma

  • Etretinate therapy of solar-related kerato acanthoma [6].
  • After surgical therapy a circumscribed relapse of viral acanthoma developed, which responded favourably to a combined antiviral and antiproliferative therapy with acitretin perorally and interferon, first subcutaneously, later intralesionally for 3 months [7].
 

Analytical, diagnostic and therapeutic context of Acanthoma

References

  1. Long-term carcinogenicity bioassays on styrene administered by inhalation, ingestion and injection and styrene oxide administered by ingestion in Sprague-Dawley rats, and para-methylstyrene administered by ingestion in Sprague-Dawley rats and Swiss mice. Conti, B., Maltoni, C., Perino, G., Ciliberti, A. Ann. N. Y. Acad. Sci. (1988) [Pubmed]
  2. Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency. Gallagher, R.C., Hay, T., Meniel, V., Naughton, C., Anderson, T.J., Shibata, H., Ito, M., Clevers, H., Noda, T., Sansom, O.J., Mason, J.O., Clarke, A.R. Oncogene (2002) [Pubmed]
  3. Immunohistochemical characterization of keratin expression in clear cell acanthoma. Ohnishi, T., Watanabe, S. Br. J. Dermatol. (1995) [Pubmed]
  4. Large-cell acanthoma of the skin. A study by image analysis cytometry and immunohistochemistry. Argenyi, Z.B., Huston, B.M., Argenyi, E.E., Maillet, M.W., Hurt, M.A. The American Journal of dermatopathology. (1994) [Pubmed]
  5. Epidermolytic acanthoma does not contain human papillomavirus DNA. Leonardi, C., Zhu, W., Kinsey, W., Penneys, N.S. J. Cutan. Pathol. (1991) [Pubmed]
  6. Etretinate therapy of solar-related kerato acanthoma. Watson, A.B. Australas. J. Dermatol. (1993) [Pubmed]
  7. Demonstration of HPV 24 in long-standing Heck's disease with malignant transformation. Niebrügge, B., Villiers, E., Gerlach, K., Franke, I., Gollnick, H. European journal of dermatology : EJD. (1999) [Pubmed]
 
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