Disease relevance of Granulomatosis, Orofacial

• Granulomatous cheilitis, Melkersson-Rosenthal syndrome, and orofacial granulomatosis [1].
• GC is the most frequent sign of orofacial granulomatosis, a disorder under which also encompasses sarcoidosis, Crohn's disease, atypical tuberculosis, Anderson-Fabry disease, possibly some allergic reactions, and Melkersson-Rosenthal syndrome (MRS) [2].

High impact information on Granulomatosis, Orofacial

• Intralesional steroid injection after nerve-block in orofacial granulomatosis [3].
• In all cases Melkersson-Rosenthal syndrome (MRS) was diagnosed both clinically and histologically, excluding other causes of orofacial granulomatosis (OFG) [4].
• CONCLUSION--Intralesional triamcinolone reduces lip swelling in patients with orofacial granulomatosis [5].
• To our knowledge this is the first report describing the use of methotrexate for treatment of orofacial granulomatosis caused by underlying Crohn's disease [6].
• Thalidomide should be considered an effective therapy for the short-term treatment of severe orofacial granulomatosis in appropriately counseled patients [7].

Chemical compound and disease context of Granulomatosis, Orofacial

• Monosodium glutamate-related orofacial granulomatosis. Review and case report [8].

Gene context of Granulomatosis, Orofacial

• The increased prevalence of atopy in patients with orofacial granulomatosis and the association with food intolerance suggests the possibility of a role for allergy in at least some cases [9].

References