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MeSH Review:

Intensive Care Units

Mir, N. et al., Siobal, M.S. et al., Landt, M. et al., Jones, R.N. et al., Jaksic, T. et al., et al.

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High impact information on Intensive Care Units

Use of APACHE II severity of disease classification to identify intensive-care-unit patients who would not benefit from total parenteral nutrition [1].
Postabsorptive proline flux, oxidation, and endogenous biosynthesis were determined in five severely burned intensive-care-unit patients (mean age 27 y) and in six healthy, young-adult control subjects [2].
Blood gases and iCa results on CNLZ-heparinized specimens from intensive-care-unit patients also compared well with specimens anticoagulated with a preparation of heparin (EB heparin) in which calcium has been added to balance the calcium-binding capacity [3].
A total of 1,914 swabs from different sample sites of 81 patients were dipped into SSMAC tubes, and after 24 h of incubation (in an incubator located near the intensive-care unit), an evident color change was considered by the intensive-care-unit personnel to be an MRSA alarm [4].
These third-generation cephalosporin differences become more important since some agents (ceftazidime) have readily selected type-I enzyme mutants among intensive-care-unit respiratory tract pathogens at our institution [5].

Associations of Intensive Care Units with chemical compounds

In comparison with healthy donors, C3a levels and the C3a/C3 ratio of intensive-care-unit patients were significantly elevated (P < 0.0001) on admission [6].
We prospectively evaluated the use of dexmedetomidine to facilitate the withdrawal of mechanical ventilation and extubation in 5 trauma/surgical intensive-care-unit patients who had failed previous weaning attempts due to agitation and hyperdynamic cardiopulmonary response [7].

Gene context of Intensive Care Units

There was no treatment-related mortality in either arm, and the use of PEG-IL-2 resulted in a significant decrease in the need for intensive-care-unit care [8].

References

Use of APACHE II severity of disease classification to identify intensive-care-unit patients who would not benefit from total parenteral nutrition. Chang, R.W., Jacobs, S., Lee, B. Lancet (1986) [Pubmed]
Proline metabolism in adult male burned patients and healthy control subjects. Jaksic, T., Wagner, D.A., Burke, J.F., Young, V.R. Am. J. Clin. Nutr. (1991) [Pubmed]
Interference in ionized calcium measurements by heparin salts. Landt, M., Hortin, G.L., Smith, C.H., McClellan, A., Scott, M.G. Clin. Chem. (1994) [Pubmed]
Soft salt-mannitol agar-cloxacillin test: a highly specific bedside screening test for detection of colonization with methicillin-resistant Staphylococcus aureus. Mir, N., Sánchez, M., Baquero, F., López, B., Calderón, C., Cantón, R. J. Clin. Microbiol. (1998) [Pubmed]
New insights into the activity of third-generation cephalosporins against pneumonia-causing bacteria. Jones, R.N., Erwin, M.E., Bale, M. Diagn. Microbiol. Infect. Dis. (1992) [Pubmed]
Circulating complement proteins in patients with sepsis or systemic inflammatory response syndrome. Stöve, S., Welte, T., Wagner, T.O., Kola, A., Klos, A., Bautsch, W., Köhl, J. Clin. Diagn. Lab. Immunol. (1996) [Pubmed]
Use of dexmedetomidine to facilitate extubation in surgical intensive-care-unit patients who failed previous weaning attempts following prolonged mechanical ventilation: a pilot study. Siobal, M.S., Kallet, R.H., Kivett, V.A., Tang, J.F. Respiratory care. (2006) [Pubmed]
The use of polyethylene glycol-modified interleukin-2 (PEG-IL-2) in the treatment of patients with metastatic renal cell carcinoma and melanoma. A phase I study and a randomized prospective study comparing IL-2 alone versus IL-2 combined with PEG-IL-2. Yang, J.C., Topalian, S.L., Schwartzentruber, D.J., Parkinson, D.R., Marincola, F.M., Weber, J.S., Seipp, C.A., White, D.E., Rosenberg, S.A. Cancer (1995) [Pubmed]

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