Disease relevance of Parenteral Nutrition, Total

• Insulin-induced hypoglycemia also occurred during treatment of hyperkalemia (eight patients) or during hyperglycemia related to total parenteral nutrition (six patients) [1].
• CONCLUSIONS: Total parenteral nutrition does not influence the overall mortality rate of surgical or critically ill patients [2].
• Hypokalemic rhabdomyolysis and acute renal failure. Occurrence following total parenteral nutrition [3].
• A patient given long-term total parenteral nutrition acquired a zinc deficiency severe enough to cause typical cutaneous manifestations of acrodermatitis enteropathica [4].
• After complete bowel resection and five months of total parenteral nutrition, severe glucose intolerance, weight loss, and a metabolic encephalopathy-like confusional state developed in a patient [5].

Psychiatry related information on Parenteral Nutrition, Total

• In the clinical setting, Clinical Nutrition Research Unit Nutritional Support Services assist in the care of patients receiving total parenteral nutrition and those with anorexia nervosa, burns, cancer, and a spectrum of nutrition-related problems [6].
• The total parenteral nutrition (TPN) model allows examination of how eliminating the growth-promoting signals stimulated by luminal nutrients, without the confounding factor of malnutrition due to food deprivation, influences enterocyte renewal [7].
• Initial conservative treatment consisted of tube thoracostomy drainage (mean duration: 13.3 days; range: 1 to 62 days; mean total volume: 4,030 mL) and dietary modification (low-fat diet, total parenteral nutrition) [8].
• Wernicke's encephalopathy during total parenteral nutrition: observation in one case [9].
• Differences in gender-related feeding patterns have also been established following a variety of experimental manipulations, such as hypothalamic lesions, nicotine infusion, and total parenteral nutrition administration [10].

High impact information on Parenteral Nutrition, Total

• Perioperative total parenteral nutrition in surgical patients [11].
• RESULTS--Case patients were more likely than controls to have had therapy via a CVC (11/11 vs 14/32; odds ratio [OR] undefined; P < .001) or total parenteral nutrition and intralipid therapy (TPN/IL) (9/11 vs 3/32; OR, 43.5; 95% confidence interval [CI], 4.9 to 510.0) [12].
• Total parenteral nutrition (TPN) using glucose as nonprotein calories was associated with increases in O2 consumption (VO2) and CO2 production (VCO2) [13].
• Heparin insensitivity after prolonged total parenteral nutrition. Probable acquired deficiency of antithrombin III [14].
• After two weeks of intravenous hyperalimentation, increasing serum transferrin levels, total lymphocyte counts, and, to a lesser extent, arm muscle circumferences predicted an improved quality of survival, whereas declines in these factors were seen in patients who died [15].

Chemical compound and disease context of Parenteral Nutrition, Total

• When no food is present in the intestine, as during periods of total parenteral nutrition, both normal individuals and patients with familiar hypercholesterolemia show a pronounced lowering of their serum cholesterol [16].
• In a prospective protocol, plasma tocopherols, selenium (Se), Se-dependent glutathione peroxidase, platelet aggregation and erythrocyte hemolysis were measured in 23 control subjects, and 15 patients receiving total parenteral nutrition (TPN), before and after 2 wk of TPN unsupplemented with vitamin E and Se [17].
• Hypomagnesemia resulted from debilitating intestinal disease in both patients and apparently was aggravated in one case by failure to add magnesium sulfate to the patient's regimen for total parenteral nutrition [18].
• OBJECTIVE: Glutamine (Gln)-supplemented total parenteral nutrition (TPN) improves clinical outcome after planned surgery, but the benefits of Gln-TPN for critically ill (intensive care unit; ICU) patients are still debated [19].
• Having recently demonstrated that taurine supplementation prevents total parenteral nutrition (TPN)-induced cholestasis, we chose to use this model to examine plasma membrane composition in relation to bile formation [20].

Biological context of Parenteral Nutrition, Total

• Energy expenditure before receiving total parenteral nutrition was only 4.6% above basal, and did not rise significantly during any of the regimens [21].
• Cholestasis of total parenteral nutrition: bile acid and bile lipid metabolism in parenterally nourished rats [22].
• Metabolic effects of total parenteral nutrition [23].
• Impairment of mucosal immunity by total parenteral nutrition: requirement for IgA in murine nasotracheal anti-influenza immunity [24].
• Effect of total parenteral nutrition plus morphine on bacterial translocation in rats [25].

Anatomical context of Parenteral Nutrition, Total

• Of these patients, 25 (23%) developed gallbladder disease after the initiation of total parenteral nutrition [26].
• In previous communications we have reported using the rat fed by total parenteral nutrition to examine the effects of the absence of food from the gut on functional and structural parameters of the gastrointestinal tract [27].
• The chyle triglyceride while on total parenteral nutrition, which presumably originates from both the intestine and plasma, contained more long-chain unsaturated fatty acids than the circulating serum triglyceride [28].
• Thrombogenicity of total parenteral nutrition solutions: II. Effect on induction of endothelial cell procoagulant activity [29].
• In each of seven infants fed with total parenteral nutrition for a mean of 5 mo (range 1.5-10 mo), basal and maximal gastric acid secretion increased after a 6-8-wk trial of enteral feeding, a highly significant difference [30].

Associations of Parenteral Nutrition, Total with chemical compounds

• Respiratory changes induced by the large glucose loads of total parenteral nutrition [13].
• Parenteral glutamine dipeptide improves nitrogen balance in postoperative patients on total parenteral nutrition (TPM) [31].
• Manganese intoxication during total parenteral nutrition [32].
• Choline deficiency associated with total parenteral nutrition [33].
• Serum apolipoprotein A-IV and lipoprotein cholesterol in patients undergoing total parenteral nutrition [34].

Gene context of Parenteral Nutrition, Total

• Moreover, GLP-2 prevents intestinal hypoplasia resulting from total parenteral nutrition [35].
• Insulin-like growth factor-I (IGF-I) responses in rats maintained with intravenous or intragastric infusion of total parenteral nutrition solutions containing medium- or long-chain triglyceride emulsions [36].
• The results suggest that under the present circumstances neither lipoprotein lipase activity nor carnitine resources are rate-limiting for the utilization of fat in newborn infants during total parenteral nutrition [37].
• To assess these determinants of fat utilization during total parenteral nutrition, lipoprotein and hepatic lipase activities and carnitine concentrations of nine newborn infants, operated on because of gastrointestinal anomalies during the first day of life, were measured with specific methods [37].
• We have therefore quantitated LCAT activity in eleven premature infants maintained on total parenteral nutrition (TPN) [38].

Analytical, diagnostic and therapeutic context of Parenteral Nutrition, Total

• Enteral feeding was started post-operatively within 18 h, was well-tolerated, and of comparable efficacy to total parenteral nutrition [39].
• From most likely to least likely the order is: blood products, haemodialysis, intravenous vasopressors, total parenteral nutrition, antibiotics, mechanical ventilation, tube feedings, and intravenous fluids [40].
• Twelve patients admitted for elective resection of carcinoma of colon or rectum were allocated at random to experimental and control groups (six in each) and received a total parenteral nutrition regimen providing 230 mg N/kg and 166 KJ/kg daily over the first 5 postoperative days [41].
• The effect of metronidazole on liver function tests was studied in patients given total parenteral nutrition (TPN) for an acute attack of Crohn's disease [42].
• Comparison of enteral feeding and total parenteral nutrition after liver transplantation [39].

References