Chemical Compound Review:
AC1O4WLL propylN-[(2S,3R)-3-hydroxy-3- [5-[[4-(2H...
Synonyms:
- A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Humbles, A.A., Lu, B., Nilsson, C.A., Lilly, C., Israel, E., Fujiwara, Y., Gerard, N.P., Gerard, C. Nature (2000)
- Anaphylatoxin C3a enhances mucous glycoprotein release from human airways in vitro. Marom, Z., Shelhamer, J., Berger, M., Frank, M., Kaliner, M. J. Exp. Med. (1985)
- An unexpected role for the anaphylatoxin C5a receptor in allergic sensitization. Lambrecht, B.N. J. Clin. Invest. (2006)
- Preliminary report: complement activation in wasp-sting anaphylaxis. van der Linden, P.W., Hack, C.E., Kerckhaert, J.A., Struyvenberg, A., van der Zwan, J.C. Lancet (1990)
- Complement in allergy and asthma. Gerard, N.P., Gerard, C. Curr. Opin. Immunol. (2002)
- Cerebrospinal fluid C3a increases with age, but does not increase further in Alzheimer's disease. Loeffler, D.A., Brickman, C.M., Juneau, P.L., Perry, M.F., Pomara, N., Lewitt, P.A. Neurobiol. Aging (1997)
- Anti-analgesic and anti-amnesic effect of complement C3a. Jinsmaa, Y., Takahashi, M., Takahashi, M., Yoshikawa, M. Life Sci. (2000)
- Increased expression of an adhesion-promoting surface glycoprotein in the granulocytopenia of hemodialysis. Arnaout, M.A., Hakim, R.M., Todd, R.F., Dana, N., Colten, H.R. N. Engl. J. Med. (1985)
- Complement activation during cardiopulmonary bypass: evidence for generation of C3a and C5a anaphylatoxins. Chenoweth, D.E., Cooper, S.W., Hugli, T.E., Stewart, R.W., Blackstone, E.H., Kirklin, J.W. N. Engl. J. Med. (1981)
- Inability of the C3a anaphylatoxin to promote cellular lysis. Goodman, M.G., Weigle, W.O., Hugli, T.E. Nature (1980)
- Complement anaphylatoxin receptors on neurons: new tricks for old receptors? Nataf, S., Stahel, P.F., Davoust, N., Barnum, S.R. Trends Neurosci. (1999)
- Cardiac dysfunction caused by purified human C3a anaphylatoxin. del Balzo, U.H., Levi, R., Polley, M.J. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Evaluation of thromboxane production and complement activation during myocardial ischemia in patients with angina pectoris. Montalescot, G., Drobinski, G., Maclouf, J., Maillet, F., Salloum, J., Ankri, A., Kazatchkine, M., Eugène, L., Thomas, D., Grosgogeat, Y. Circulation (1991)
- C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins. Elsner, J., Oppermann, M., Czech, W., Kapp, A. Blood (1994)
- C3a is a chemotaxin for human eosinophils but not for neutrophils. I. C3a stimulation of neutrophils is secondary to eosinophil activation. Daffern, P.J., Pfeifer, P.H., Ember, J.A., Hugli, T.E. J. Exp. Med. (1995)
- Human platelet activation by C3a and C3a des-arg. Polley, M.J., Nachman, R.L. J. Exp. Med. (1983)
- Anaphylatoxin-mediated regulation of the immune response. I. C3a-mediated suppression of human and murine humoral immune responses. Morgan, E.L., Weigle, W.O., Hugli, T.E. J. Exp. Med. (1982)
- F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins. Basta, M., Van Goor, F., Luccioli, S., Billings, E.M., Vortmeyer, A.O., Baranyi, L., Szebeni, J., Alving, C.R., Carroll, M.C., Berkower, I., Stojilkovic, S.S., Metcalfe, D.D. Nat. Med. (2003)
- The proinflammatory mediators C3a and C5a are essential for liver regeneration. Strey, C.W., Markiewski, M., Mastellos, D., Tudoran, R., Spruce, L.A., Greenbaum, L.E., Lambris, J.D. J. Exp. Med. (2003)
- Modulation of human lymphocyte function by C3a and C3a(70-77). Payan, D.G., Trentham, D.E., Goetzl, E.J. J. Exp. Med. (1982)
- Anaphylatoxin-induced histamine release with human leukocytes: studies of C3a leukocyte binding and histamine release. Glovsky, M.M., Hugli, T.E., Ishizaka, T., Lichtenstein, L.M., Erickson, B.W. J. Clin. Invest. (1979)
- Induction of interleukin-8 expression during cardiopulmonary bypass. Kalfin, R.E., Engelman, R.M., Rousou, J.A., Flack, J.E., Deaton, D.W., Kreutzer, D.L., Das, D.K. Circulation (1993)
- Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1. Reca, R., Mastellos, D., Majka, M., Marquez, L., Ratajczak, J., Franchini, S., Glodek, A., Honczarenko, M., Spruce, L.A., Janowska-Wieczorek, A., Lambris, J.D., Ratajczak, M.Z. Blood (2003)
- Platelet-activating factor induces mediator release by human basophils primed with IL-3, granulocyte-macrophage colony-stimulating factor, or IL-5. Brunner, T., de Weck, A.L., Dahinden, C.A. J. Immunol. (1991)
- The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen. Kawamoto, S., Yalcindag, A., Laouini, D., Brodeur, S., Bryce, P., Lu, B., Humbles, A.A., Oettgen, H., Gerard, C., Geha, R.S. J. Clin. Invest. (2004)
- C4a: the third anaphylatoxin of the human complement system. Gorski, J.P., Hugli, T.E., Müller-Eberhard, H.J. Proc. Natl. Acad. Sci. U.S.A. (1979)
- Activation of complement and kinin systems after thrombolytic therapy in patients with acute myocardial infarction. A comparison between streptokinase and recombinant tissue-type plasminogen activator. Agostoni, A., Gardinali, M., Frangi, D., Cafaro, C., Conciato, L., Sponzilli, C., Salvioni, A., Cugno, M., Cicardi, M. Circulation (1994)
- Influence of temperature on neutrophil trafficking during clinical cardiopulmonary bypass. Menasché, P., Peynet, J., Haeffner-Cavaillon, N., Carreno, M.P., de Chaumaray, T., Dillisse, V., Faris, B., Piwnica, A., Bloch, G., Tedgui, A. Circulation (1995)