High impact information on Locomotion

• Thus caffeine has no effect on gamma even though it produces a dose-related increase in locomotions [1].
• L-Arginine and L-NAME increased and decreased apomorphine- or morphine-induced locomotions, respectively [2].
• In contrast, the same doses of clonidine had no effect on locomotions produced by a higher dose of amphetamine (6 mg/kg) [3].
• Administration of buspirone either did not affect (2.0 and 4.0 mg/kg) or inhibited (8.0 mg/kg) locomotions in control animals [4].
• Repeated pemoline increased locomotions and rears and produced intermittent stereotyped sniffing and licking/biting [5].

Biological context of Locomotion

• Pimozide (0.5, 0.8 and 1.3 mg/kg) had little or no effect on behaviors such as locomotions, rears, licking/biting, or stereotyped head movements but eliminated self-biting at 1.3 mg/kg [6].

Associations of Locomotion with chemical compounds

• Administration of diazepam (0.5 and 2.0 mg/kg), flumazenil (5.0 and 10.0 mg/kg) and RO 15-4513 (1.0, 2.0 and 3.0 mg/kg) either did not affect (in low doses) or inhibited (in high doses) locomotions of control animals [7].
• Valofan (250 and 500 mg/kg) always reduced spontaneous locomotion and amphetamine-induced hypermotility; after the administration of L-tryptophan (10 mg/kg) and tranylcypromine (1 mg/kg) both locomotions decreased; when administered in combination with valofan they resulted in an additive effect [8].

References