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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Factors associated with the prevalence of myopia in 6-year-olds.

PURPOSE: To describe the frequency of and risk factors associated with myopia in grade one children. METHODS: Refractive error was measured by static retinoscopy, without cycloplegia, for 10,616 children in the first year of a province-wide vision-screening program. Information on factors that might be associated with myopia was collected from parents or guardians by self-administered questionnaires distributed before the vision screening. These factors were evaluated by a case-control method. RESULTS: The prevalence of myopia, greater than -0.25 D, was 6%. The estimated relative risk of myopia was increased significantly among children whose birth weight was <2500 g and whose mothers had a history of early spectacle use. CONCLUSIONS: Results suggest that the prevalence of myopia in 6-year-old children is associated with both hereditary and nonhereditary factors. In accord with prior work, the results argue that low birth weight has a permanent influence upon eye development.[1]


  1. Factors associated with the prevalence of myopia in 6-year-olds. Robinson, B.E. Optometry and vision science : official publication of the American Academy of Optometry. (1999) [Pubmed]
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