- TNF-alpha induces apoptosis mediated by AEBSF-sensitive serine protease(s) that may involve upstream caspase-3/CPP32 protease activation in a human gastric cancer cell line. Park, I.C., Park, M.J., Choe, T.B., Jang, J.J., Hong, S.I., Lee, S.H. Int. J. Oncol. (2000)