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Chemical Compound Review

Pefabloc     4-(2- aminoethyl)benzenesulfonyl fluoride

Synonyms: AEBSF, Pefabloc SC, Lopac-A-8456, AG-K-81649, CHEMBL1096339, ...
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Disease relevance of Pefabloc


High impact information on Pefabloc


Biological context of Pefabloc


Anatomical context of Pefabloc


Associations of Pefabloc with other chemical compounds


Gene context of Pefabloc


Analytical, diagnostic and therapeutic context of Pefabloc

  • All were processed by using a standard protocol of Liberase perfusion with Pefabloc by way of the duct, gentle mechanical dissociation, and Ficoll gradient purification [26].


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  9. Multiple substrates for paraoxonase-1 during oxidation of phosphatidylcholine by peroxynitrite. Ahmed, Z., Ravandi, A., Maguire, G.F., Emili, A., Draganov, D., La Du, B.N., Kuksis, A., Connelly, P.W. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  10. TNF-alpha induces apoptosis mediated by AEBSF-sensitive serine protease(s) that may involve upstream caspase-3/CPP32 protease activation in a human gastric cancer cell line. Park, I.C., Park, M.J., Choe, T.B., Jang, J.J., Hong, S.I., Lee, S.H. Int. J. Oncol. (2000) [Pubmed]
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  13. Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1. Waki, H., Yamauchi, T., Kamon, J., Kita, S., Ito, Y., Hada, Y., Uchida, S., Tsuchida, A., Takekawa, S., Kadowaki, T. Endocrinology (2005) [Pubmed]
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  17. Metalloendopeptidase EC is necessary for Alzheimer's amyloid-beta peptide degradation. Yamin, R., Malgeri, E.G., Sloane, J.A., McGraw, W.T., Abraham, C.R. J. Biol. Chem. (1999) [Pubmed]
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  19. PAF-degrading acetylhydrolase is preferentially associated with dense LDL and VHDL-1 in human plasma. Catalytic characteristics and relation to the monocyte-derived enzyme. Tselepis, A.D., Dentan, C., Karabina, S.A., Chapman, M.J., Ninio, E. Arterioscler. Thromb. Vasc. Biol. (1995) [Pubmed]
  20. Inhibitors of trypsin-like serine proteases inhibit processing of the caspase Nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support. Stefanis, L., Troy, C.M., Qi, H., Greene, L.A. J. Neurochem. (1997) [Pubmed]
  21. Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids. Wartenberg, M., Hoffmann, E., Schwindt, H., Grünheck, F., Petros, J., Arnold, J.R., Hescheler, J., Sauer, H. FEBS Lett. (2005) [Pubmed]
  22. Activation of human matrix metalloproteinase 2 by gingival crevicular fluid and Porphyromonas gingivalis. Grayson, R., Douglas, C.W., Heath, J., Rawlinson, A., Evans, G.S. Journal of clinical periodontology. (2003) [Pubmed]
  23. Role of reactive oxygen species and NAD(P)H oxidase in alpha(1)-adrenoceptor signaling in adult rat cardiac myocytes. Xiao, L., Pimentel, D.R., Wang, J., Singh, K., Colucci, W.S., Sawyer, D.B. Am. J. Physiol., Cell Physiol. (2002) [Pubmed]
  24. Proteolytic activity of bovine lactoferrin. Massucci, M.T., Giansanti, F., Di Nino, G., Turacchio, M., Giardi, M.F., Botti, D., Ippoliti, R., De Giulio, B., De Giulio, B., Siciliano, R.A., Siciliano, R., Donnarumma, G., Valenti, P., Bocedi, A., Polticelli, F., Ascenzi, P., Antonini, G. Biometals (2004) [Pubmed]
  25. Enzymatic cleavage as a processing step in the maturation of Muc4/sialomucin complex. Soto, P., Zhang, J., Carraway, K.L. J. Cell. Biochem. (2006) [Pubmed]
  26. Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method. Tsujimura, T., Kuroda, Y., Kin, T., Avila, J.G., Rajotte, R.V., Korbutt, G.S., Ryan, E.A., Shapiro, A.M., Lakey, J.R. Transplantation (2002) [Pubmed]
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