- The PC-1 Q121 allele is exceptionally prevalent in the Dominican Republic and is associated with type 2 diabetes. Hamaguchi, K., Terao, H., Kusuda, Y., Yamashita, T., Hazoury Bahles, J.A., Cruz LL, M., Brugal V, L.I., Jongchong W, B., Yoshimatsu, H., Sakata, T. J. Clin. Endocrinol. Metab. (2004)