- K(ATP) channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes. Kanezaki, Y., Obata, T., Matsushima, R., Minami, A., Yuasa, T., Kishi, K., Bando, Y., Uehara, H., Izumi, K., Mitani, T., Matsumoto, M., Takeshita, Y., Nakaya, Y., Matsumoto, T., Ebina, Y. Endocr. J. (2004)