- The two thrombospondin type I repeat domains of the heparin-binding growth-associated molecule bind to heparin/heparan sulfate and regulate neurite extension and plasticity in hippocampal neurons. Raulo, E., Tumova, S., Pavlov, I., Pekkanen, M., Hienola, A., Klankki, E., Kalkkinen, N., Taira, T., Kilpelaïnen, I., Rauvala, H. J. Biol. Chem. (2005)