- Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel. Nakagawa, K., Holla, V.R., Wei, Y., Wang, W.H., Gatica, A., Wei, S., Mei, S., Miller, C.M., Cha, D.R., Price, E., Zent, R., Pozzi, A., Breyer, M.D., Guan, Y., Falck, J.R., Waterman, M.R., Capdevila, J.H. J. Clin. Invest. (2006)