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Misra, U.K. et al.

Usha K. Misra, Pradeep K. Maurya, Jayantee Kalita, Rakesh K. Gupta,

Stiff limb syndrome: end of spectrum or a separate entity?

BACKGROUND: Stiff-person syndrome is a rare disorder characterized by rigidity of axial or limb muscles with episodes of co-contraction of agonist and antagonist muscles during the spasms. In some patients axial or limb involvement may predominate and may have unusual manifestations. DESIGN: Case report. SETTING: Tertiary care teaching hospital. PATIENT: A 42-year-old farmer presented with seasonal occurrence of hiccup and vomiting during summer months for the last 3 years. He had painful lower limb spasms lasting for 2-3 minutes every 10-15 minutes for the past 20 days. His neurological examination was normal, erythrocyte sedimentation rate (ESR) was 50 mm at 1st hour, and cerebrospinal fluid protein 78 mg/dL without pleocytosis. Radiograph of chest, abdominal ultrasound, and craniospinal magnetic resonance imaging were normal. The patient improved on diazepam. CONCLUSION: Our patient is a forme fruste of stiff person syndrome with hiccups and vomiting due to diaphragmatic spasm.[1]

References

Stiff limb syndrome: end of spectrum or a separate entity? Misra, U.K., Maurya, P.K., Kalita, J., Gupta, R.K. Pain. Med (2009) [Pubmed]

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