The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 

The role of the blood glucose level in determining voluntary ethanol consumption in the LACG and diabetogenic C57BL strains of mice.

The influence of the blood glucose level ( BGL) on the voluntary consumption of ethanol by two strains of mice has been investigated. LACG mice show an aversion towards ethanol whereas C57BL mice which are mildly hyperglycaemic show a preference for ethanol. Chronic compulsory ethanol drinking produced hypoglycaemia only in C57BL mice. The oral antidiabetic drugs phenformin and glibenclamide lowered the BGL of C57BL mice which then showed an aversion to ethanol. Raising the BGL of LACG mice by acute alloxan or streptozotocin treatment did not reduce ethanol aversion significantly, but alloxan significantly increased total fluid intake. Diazoxide chronically increased the BGL and slightly increased ethanol consumption in LACG mice. It is concluded that the BGL in C57BL mice may be a factor in determining their innate preference for alcohol. The relationship between alcoholism and diabetes is discussed.[1]

References

  1. The role of the blood glucose level in determining voluntary ethanol consumption in the LACG and diabetogenic C57BL strains of mice. Connelly, D.M., Unwin, J.W., Taberner, P.V. Biochem. Pharmacol. (1983) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities