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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3.

We have isolated and characterized cDNA clones encoding a novel human homeobox gene, MOX2, the homologue of the murine mox-2 gene. The MOX2 protein contains all of the characteristic features of Mox-2 proteins of other vertebrate species, namely the homeobox, the polyhistidine stretch, and a number of potential serine/threonine phosphorylation sites. The homeodomain of MOX2 protein is identical to all other vertebrate species reported so far (rodents and amphibians). Outside the homeodomain, Mox-2 proteins share a high degree of identity, except for a few amino acid differences encountered between the human and the rodent polypeptides. A polyhistidine stretch of 12 amino acids in the N terminal region of the protein is also conserved among humans, rodents, and (only partly) amphibians. The chromosomal position of MOX2 was assigned to 7p22.1-p21.3.[1]

References

  1. Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3. Grigoriou, M., Kastrinaki, M.C., Modi, W.S., Theodorakis, K., Mankoo, B., Pachnis, V., Karagogeos, D. Genomics (1995) [Pubmed]
 
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