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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Ocular dimensions and refraction in Tibetan children.

A cross-sectional study of 404 Tibetan children (212 males, 192 females) aged 6 to 16 years was conducted in the Bouda region of Kathmandu, Napal in April, 1992. Examination procedures included retinoscopy (1% cyclopentolate HCl), keratometry A-scan ultrasonography, and video ophthalmophakometry. The mean refractive error was +1.11 D (SD: 0.56 D) at age 6 years decreasing to +0.63 D (SD: 0.34 D) at age 16 years with a prevalence of myopia in this group of 3.9%. Most children examined had low refractive errors, with 95.5% having errors in the range -0.50 to +1.50 D. Crystalline lens power decreased by 2.59 D, with an associated increase in its anterior radius of curvature of 1.98 mm and 0.49 mm in its posterior radius of curvature over the age range studied. Vitreous chamber depth increased by 0.69 mm, but no significant changes were recorded in anterior chamber depth, lens thickness, or corneal curvature. We conclude that the balance between the decrease in crystalline lens power and the increase in vitreous length is the major factor in maintaining the tendency to emmetropia in these children.[1]


  1. Ocular dimensions and refraction in Tibetan children. Garner, L.F., Yap, M.K., Kinnear, R.F., Frith, M.J. Optometry and vision science : official publication of the American Academy of Optometry. (1995) [Pubmed]
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