Gene Review:
CBX8 - chromobox homolog 8
Homo sapiens
Synonyms:
Chromobox protein homolog 8, HPC3, PC3, Pc3, Polycomb 3 homolog, ...
- Phase-variable expression of lipopolysaccharide contributes to the virulence of legionella pneumophila. Lüneberg, E., Zähringer, U., Knirel, Y.A., Steinmann, D., Hartmann, M., Steinmetz, I., Rohde, M., Köhl, J., Frosch, M. J. Exp. Med. (1998)
- Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells. Ghosh, J., Myers, C.E. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Isolation of a prostate carcinoma cell proliferation-inhibiting factor from human seminal plasma and its similarity to transforming growth factor beta. Lokeshwar, B.L., Block, N.L. Cancer Res. (1992)
- Expression of the interleukin 6 receptor and interleukin 6 in prostate carcinoma cells. Siegall, C.B., Schwab, G., Nordan, R.P., FitzGerald, D.J., Pastan, I. Cancer Res. (1990)
- A spontaneous internal deletion of the c-myb protooncogene enhances transcriptional activation in bovine T lymphoma cells. Ishiguro, N., Ohzono, T., Shinagawa, T., Horiuchi, M., Shinagawa, M. J. Biol. Chem. (1994)
- Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway. Rouault, J.P., Falette, N., Guéhenneux, F., Guillot, C., Rimokh, R., Wang, Q., Berthet, C., Moyret-Lalle, C., Savatier, P., Pain, B., Shaw, P., Berger, R., Samarut, J., Magaud, J.P., Ozturk, M., Samarut, C., Puisieux, A. Nat. Genet. (1996)
- Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus. Dietrich, N., Bracken, A.P., Trinh, E., Schjerling, C.K., Koseki, H., Rappsilber, J., Helin, K., Hansen, K.H. EMBO J. (2007)
- Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide. Chen, K., Arnold, F.H. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Estradiol inhibits growth of hormone-nonresponsive PC3 human prostate cancer cells. Carruba, G., Pfeffer, U., Fecarotta, E., Coviello, D.A., D'Amato, E., Lo Castro, M., Vidali, G., Castagnetta, L. Cancer Res. (1994)
- Human prostate cancer expresses the low affinity insulin-like growth factor binding protein IGFBP-rP1. Degeorges, A., Wang, F., Frierson, H.F., Seth, A., Chung, L.W., Sikes, R.A. Cancer Res. (1999)
- Melatonin receptors in PC3 human prostate tumor cells. Gilad, E., Laufer, M., Matzkin, H., Zisapel, N. J. Pineal Res. (1999)
- Inhibition of export of fibroblast growth factor-2 (FGF-2) from the prostate cancer cell lines PC3 and DU145 by Anvirzel and its cardiac glycoside component, oleandrin. Smith, J.A., Madden, T., Vijjeswarapu, M., Newman, R.A. Biochem. Pharmacol. (2001)
- Metabolomic differentiation of deer antlers of various origins by 1H NMR spectrometry and principal components analysis. Choi, H.K., Kim, K.H., Kim, K.H., Kim, Y.S., Lee, M.W., Whang, W.K. Journal of pharmaceutical and biomedical analysis. (2006)
- Autonomous growth of androgen-independent human prostatic carcinoma cells: role of transforming growth factor alpha. Hofer, D.R., Sherwood, E.R., Bromberg, W.D., Mendelsohn, J., Lee, C., Kozlowski, J.M. Cancer Res. (1991)
- Human prostatic cancer cells, PC3, elaborate mitogenic activity which selectively stimulates human bone cells. Perkel, V.S., Mohan, S., Herring, S.J., Baylink, D.J., Linkhart, T.A. Cancer Res. (1990)
- Defects of DNA mismatch repair in human prostate cancer. Chen, Y., Wang, J., Fraig, M.M., Metcalf, J., Turner, W.R., Bissada, N.K., Watson, D.K., Schweinfest, C.W. Cancer Res. (2001)
- The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3. García-Cuéllar, M.P., Zilles, O., Schreiner, S.A., Birke, M., Winkler, T.H., Slany, R.K. Oncogene (2001)
- Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Kretzschmar, M., Meisterernst, M., Roeder, R.G. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Pharmacodynamics of immediate and delayed effects of paclitaxel: role of slow apoptosis and intracellular drug retention. Au, J.L., Li, D., Gan, Y., Gao, X., Johnson, A.L., Johnston, J., Millenbaugh, N.J., Jang, S.H., Kuh, H.J., Chen, C.T., Wientjes, M.G. Cancer Res. (1998)
- Epidermal growth factor receptor monoclonal antibody inhibits constitutive receptor phosphorylation, reduces autonomous growth, and sensitizes androgen-independent prostatic carcinoma cells to tumor necrosis factor alpha. Fong, C.J., Sherwood, E.R., Mendelsohn, J., Lee, C., Kozlowski, J.M. Cancer Res. (1992)
- Antiproliferative and angiostatic activity of suramin analogues. Firsching, A., Nickel, P., Mora, P., Allolio, B. Cancer Res. (1995)
- Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line. Urasaki, Y., Laco, G.S., Pourquier, P., Takebayashi, Y., Kohlhagen, G., Gioffre, C., Zhang, H., Chatterjee, D., Pantazis, P., Pommier, Y. Cancer Res. (2001)
- Use of camptothecin-resistant mammalian cell lines to evaluate the role of topoisomerase I in the antiproliferative activity of the indolocarbazole, NB-506, and its topoisomerase I binding site. Urasaki, Y., Laco, G., Takebayashi, Y., Bailly, C., Kohlhagen, G., Pommier, Y. Cancer Res. (2001)
- HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. Bárdos, J.I., Saurin, A.J., Tissot, C., Duprez, E., Freemont, P.S. J. Biol. Chem. (2000)
- Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion. Sato, N., Maehara, N., Mizumoto, K., Nagai, E., Yasoshima, T., Hirata, K., Tanaka, M. Cancer (2001)
- In vitro expression of endothelin-1 (ET-1) and the ETA and ETB ET receptors by the prostatic epithelium and stroma. Grant, E.S., Brown, T., Roach, A., Williams, B.C., Habib, F.K. J. Clin. Endocrinol. Metab. (1997)