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Chemical Compound Review

Toluquinone     2-methylcyclohexa-2,5-diene- 1,4-dione

Synonyms: Tolylquinone, Methylquinone, p-Toluquinone, NSC-1, NSC1, ...
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Disease relevance of p-Toluquinone

  • To evaluate the plausibility of this hypothesis, female yellow fever mosquitoes (Aedes aegypti) were presented with two millipede secretory compounds, 2-methyl-1,4-benzoquinone and 2-methoxy-3-methyl-1,4-benzoquinone, on nylon-reinforced silicone membranes placed over wells filled with human blood, a highly preferred food [1].

Psychiatry related information on p-Toluquinone


High impact information on p-Toluquinone

  • Conversely, no radical was detected with either CDH or CBQR upon the addition of methyl-1,4-benzoquinone [3].
  • Similar reaction rates and activation energies were determined for methyl-1,4-benzoquinone with both CDH and CBQR, whereas the rate of iron reduction by CDH was five times higher than by CBQR, and its activation energy was 38 kJ/mol lower than that of CBQR [3].
  • Methylhydroquinone caused Cu(II)-mediated DNA damage, whereas methylbenzoquinone did only in the presence of NADH [4].
  • The purpose of this study was to determine if OMX-2, a methylquinone system designed to shuttle electrons from mitochondrial complexes, was able to target mitochondria in cancer cells and trigger cell death [5].
  • TQ exposure assay is a new, easily testable, and low-cost method for measuring rodents olfactory sensitivity relevant for the analysis of the pharmacological agents, lesions and transgenesis [2].


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