Disease relevance of p-Toluquinone

• To evaluate the plausibility of this hypothesis, female yellow fever mosquitoes (Aedes aegypti) were presented with two millipede secretory compounds, 2-methyl-1,4-benzoquinone and 2-methoxy-3-methyl-1,4-benzoquinone, on nylon-reinforced silicone membranes placed over wells filled with human blood, a highly preferred food [1].

Psychiatry related information on p-Toluquinone

• Toluquinone-exposed mice showed a subtle yet significant decrease of pain threshold [2].

High impact information on p-Toluquinone

• Conversely, no radical was detected with either CDH or CBQR upon the addition of methyl-1,4-benzoquinone [3].
• Similar reaction rates and activation energies were determined for methyl-1,4-benzoquinone with both CDH and CBQR, whereas the rate of iron reduction by CDH was five times higher than by CBQR, and its activation energy was 38 kJ/mol lower than that of CBQR [3].
• Methylhydroquinone caused Cu(II)-mediated DNA damage, whereas methylbenzoquinone did only in the presence of NADH [4].
• The purpose of this study was to determine if OMX-2, a methylquinone system designed to shuttle electrons from mitochondrial complexes, was able to target mitochondria in cancer cells and trigger cell death [5].
• TQ exposure assay is a new, easily testable, and low-cost method for measuring rodents olfactory sensitivity relevant for the analysis of the pharmacological agents, lesions and transgenesis [2].

References