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Chemical Compound Review

Toluquinol     2-methylbenzene-1,4-diol

Synonyms: p-Toluquinol, PubChem14584, SureCN36349, CHEMBL450917, NSC-4962, ...
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Disease relevance of Pyrolin


High impact information on Pyrolin


Biological context of Pyrolin


  1. Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for synthesizing 4-methylresorcinol, methylhydroquinone, and pyrogallol. Vardar, G., Wood, T.K. Appl. Environ. Microbiol. (2004) [Pubmed]
  2. Possible tumor-initiating and -promoting activity of p-methylcatechol and methylhydroquinone in the pyloric mucosa of rat stomach. Furihata, C., Oguchi, S., Matsushima, T. Jpn. J. Cancer Res. (1993) [Pubmed]
  3. Characterization of methylhydroquinone-metabolizing oxygenase genes encoded on plasmid in Burkholderia sp. NF100. Tago, K., Sato, J., Takesa, H., Kawagishi, H., Hayatsu, M. J. Biosci. Bioeng. (2005) [Pubmed]
  4. Comparison of the effects of 13 phenolic compounds in induction of proliferative lesions of the forestomach and increase in the labelling indices of the glandular stomach and urinary bladder epithelium of Syrian golden hamsters. Hirose, M., Inoue, T., Asamoto, M., Tagawa, Y., Ito, N. Carcinogenesis (1986) [Pubmed]
  5. Oxidative DNA damage induced by toluene is involved in its male reproductive toxicity. Nakai, N., Murata, M., Nagahama, M., Hirase, T., Tanaka, M., Fujikawa, T., Nakao, N., Nakashima, K., Kawanishi, S. Free Radic. Res. (2003) [Pubmed]
  6. Biotransformation of 3-methyl-4-nitrophenol, a main product of the insecticide fenitrothion, by Aspergillus niger. Kanaly, R.A., Kim, I.S., Hur, H.G. J. Agric. Food Chem. (2005) [Pubmed]
  7. Oxidative DNA damage by minor metabolites of toluene may lead to carcinogenesis and reproductive dysfunction. Murata, M., Tsujikawa, M., Kawanishi, S. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
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