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Chemical Compound Review:

Of-557 1-[8-(dimethylaminomethyl)-1- methyl-1...

Synonyms: AC1L3DYP, AC1Q1TFK, AR-1D2312, LS-143151

This record was replaced with 113786.

Little, J.S. et al., Goh, C.L., Garg, P. et al.

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Disease relevance of 1-[8-(dimethylaminomethyl)-1-methyl-1-azoniabicyclo[2.2.2]oct-7-yl]-N,N-dimethyl-methanamine

RESULTS: Of 557 cases of fungal keratitis seen during the study period, dematiaceous fungi were the etiologic agents in 88 (15.7%), after Fusarium in 210 (37.6%) and Aspergillus species in 170 cases (30.4%), respectively [1].
Of 557 patients with occupational dermatoses seen at the Middle Road Hospital, Singapore, 55.7% (310) were irritant contact dermatitis, 38.6% (215) were allergic contact dermatitis and 5.7% (32) were non contact dermatitis [2].

High impact information on 1-[8-(dimethylaminomethyl)-1-methyl-1-azoniabicyclo[2.2.2]oct-7-yl]-N,N-dimethyl-methanamine

Of 557 patients undergoing post-chemotherapy retroperitoneal lymph node dissection at our university medical center 45 (8.1%) had neoplastic elements distinct from the classical germ cell tumor types within the resected specimens [3].

References

Keratomycosis: clinical and microbiologic experience with dematiaceous fungi. Garg, P., Gopinathan, U., Choudhary, K., Rao, G.N. Ophthalmology (2000) [Pubmed]
Occupational skin disease in Singapore: epidemiology & causative agents. Goh, C.L. Ann. Acad. Med. Singap. (1987) [Pubmed]
Unusual neoplasms detected in testis cancer patients undergoing post-chemotherapy retroperitoneal lymphadenectomy. Little, J.S., Foster, R.S., Ulbright, T.M., Donohue, J.P. J. Urol. (1994) [Pubmed]

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