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Chemical Compound Review

Tyr(3)-sms     10-(4-aminobutyl)-19-[(2- amino-3-phenyl...

Synonyms: AC1L3XFS, Sdz-204-090, Sms-204-090, AR-1B9971, Sdz 204-090, ...
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Disease relevance of Tyr-3-octreotide


High impact information on Tyr-3-octreotide


Anatomical context of Tyr-3-octreotide


Associations of Tyr-3-octreotide with other chemical compounds

  • The recent availability of a Tyr3-substituted octreotide (SDZ 204-090) for radioiodination has allowed somatostatin (SRIH) receptor binding to be studied in vivo, and receptor-positive tumors of different origins to be visualized with a gamma-camera [8].

Analytical, diagnostic and therapeutic context of Tyr-3-octreotide


  1. A scintigraphic comparison of iodine-123-metaiodobenzylguanidine and an iodine-labeled somatostatin analog (Tyr-3-octreotide) in metastatic carcinoid tumors. Bomanji, J., Mather, S., Moyes, J., Ellison, D., Grossman, A., Britton, K.E., Besser, G.M. J. Nucl. Med. (1992) [Pubmed]
  2. Localisation of endocrine-related tumours with radioiodinated analogue of somatostatin. Krenning, E.P., Bakker, W.H., Breeman, W.A., Koper, J.W., Kooij, P.P., Ausema, L., Lameris, J.S., Reubi, J.C., Lamberts, S.W. Lancet (1989) [Pubmed]
  3. Somatostatin receptors are restricted to a subpopulation of osteoblast-like cells during endochondral bone formation. Mackie, E.J., Trechsel, U., Bruns, C. Development (1990) [Pubmed]
  4. Octreotide scintigraphy localizes somatostatin receptor-positive islet cell carcinomas. Becker, W., Marienhagen, J., Scheubel, R., Saptogino, A., Bakker, W.H., Breeman, W.A., Wolf, F. European journal of nuclear medicine. (1991) [Pubmed]
  5. Developmental expression of somatostatin receptors in the rat retina. Ferriero, D.M. Brain Res. Dev. Brain Res. (1992) [Pubmed]
  6. Evaluation of somatostatin receptors in human cancer. Pantev, T., Virgolini, I., Neuhold, N., Angelberger, P., Luger, A., Sinzinger, H. Wien. Klin. Wochenschr. (1991) [Pubmed]
  7. Molecular characterization of the solubilized receptor of somatostatin from rat pancreatic acinar membranes. Knuhtsen, S., Esteve, J.P., Bernadet, B., Vaysse, N., Susini, C. Biochem. J. (1988) [Pubmed]
  8. In vivo detection of somatostatin receptors in patients with functionless pituitary adenomas by means of a radioiodinated analog of somatostatin ([123I]SDZ 204-090). Faglia, G., Bazzoni, N., Spada, A., Arosio, M., Ambrosi, B., Spinelli, F., Sara, R., Bonino, C., Lunghi, F. J. Clin. Endocrinol. Metab. (1991) [Pubmed]
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