Gene Review:
Sst - somatostatin
Rattus norvegicus
Synonyms:
SS-14, SS-28, Smst, Somatostatin
- Primary structure of the gene encoding rat preprosomatostatin. Montminy, M.R., Goodman, R.H., Horovitch, S.J., Habener, J.F. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Isolation, characterization, and DNA sequence of the rat somatostatin gene. Tavianini, M.A., Hayes, T.E., Magazin, M.D., Minth, C.D., Dixon, J.E. J. Biol. Chem. (1984)
- Relative potencies of the somatostatin analogs octreotide, BIM-23014, and RC-160 on the inhibition of hormone release by cultured human endocrine tumor cells and normal rat anterior pituitary cells. Hofland, L.J., van Koetsveld, P.M., Waaijers, M., Zuyderwijk, J., Lamberts, S.W. Endocrinology (1994)
- Gene expression of hypothalamic somatostatin, growth hormone releasing factor, and their pituitary receptors in hypothyroidism. Tam, S.P., Lam, K.S., Srivastava, G. Endocrinology (1996)
- Silencing preBötzinger complex somatostatin-expressing neurons induces persistent apnea in awake rat. Tan, W., Janczewski, W.A., Yang, P., Shao, X.M., Callaway, E.M., Feldman, J.L. Nat. Neurosci. (2008)
- Effect of food deprivation on rat gastric somatostatin and gastrin release. Koop, H., Schwab, E., Arnold, R., Creutzfeldt, W. Gastroenterology (1982)
- Somatostatin receptors in the nucleus accumbens selectively mediate the stimulatory effect of somatostatin on locomotor activity in rats. Raynor, K., Lucki, I., Reisine, T. J. Pharmacol. Exp. Ther. (1993)
- The effect of REM sleep deprivation on somatostatin and growth hormone-releasing hormone gene expression in the rat hypothalamus. Toppila, J., Asikainen, M., Alanko, L., Turek, F.W., Stenberg, D., Porkka-Heiskanen, T. Journal of sleep research. (1996)
- Sleep deprivation increases somatostatin and growth hormone-releasing hormone messenger RNA in the rat hypothalamus. Toppila, J., Alanko, L., Asikainen, M., Tobler, I., Stenberg, D., Porkka-Heiskanen, T. Journal of sleep research. (1997)
- Antagonistic effects of growth hormone-releasing factor (GRF) and somatostatin on locomotor activity: GRF-induced hyperkinetic syndrome. Cacabelos, R., Niigawa, H., Alvarez, X.A., Muñoz, M.D., Nishimura, T., Rubia, F.J. Methods and findings in experimental and clinical pharmacology. (1990)
- Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Gonzalez, G.A., Montminy, M.R. Cell (1989)
- A cortical neuropeptide with neuronal depressant and sleep-modulating properties. de Lecea, L., Criado, J.R., Prospero-Garcia, O., Gautvik, K.M., Schweitzer, P., Danielson, P.E., Dunlop, C.L., Siggins, G.R., Henriksen, S.J., Sutcliffe, J.G. Nature (1996)
- Different beta-subunits determine G-protein interaction with transmembrane receptors. Kleuss, C., Scherübl, H., Hescheler, J., Schultz, G., Wittig, B. Nature (1992)
- Somatostatin stimulates Ca(2+)-activated K+ channels through protein dephosphorylation. White, R.E., Schonbrunn, A., Armstrong, D.L. Nature (1991)
- Gastric secretion and gastrin under progressive doses of somatostatin-14 and -28 administered intraperitoneally to the rat. Seefried, G., Schmidtler, J., Schwille, P.O. Peptides (1988)
- Effect of hypophysectomy and growth hormone administration on hypothalamic growth hormone-releasing hormone and somatostatin content: relationship to age-related growth rate. Leidy, J.W., McDermott, M.T., Robbins, R.J. Neuroendocrinology (1990)
- Somatostatin and gamma-aminobutyric acid inhibit interleukin-1 beta-stimulated release of interleukin-6 from rat C6 glioma cells. Spangelo, B.L., Horrell, S., Goodwin, A.L., Shroff, S., Jarvis, W.D. Neuroimmunomodulation (2004)
- Interaction of growth hormone-releasing factor and somatostatin on ulcer healing and mucosal growth in rats: role of gastrin and epidermal growth factor. Konturek, S.J., Brzozowski, T., Dembinski, A., Warzecha, Z., Konturek, P.K., Yanaihara, N. Digestion (1988)
- Reciprocal regulation of antral gastrin and somatostatin gene expression by omeprazole-induced achlorhydria. Brand, S.J., Stone, D. J. Clin. Invest. (1988)
- The somatostatin receptor subtype on rat enterochromaffinlike cells. Prinz, C., Sachs, G., Walsh, J.H., Coy, D.H., Wu, S.V. Gastroenterology (1994)
- Interrelationships between somatostatin sst2A receptors and somatostatin-containing axons in rat brain: evidence for regulation of cell surface receptors by endogenous somatostatin. Dournaud, P., Boudin, H., Schonbrunn, A., Tannenbaum, G.S., Beaudet, A. J. Neurosci. (1998)
- Somatostatin-28 encoded in a cloned cDNA obtained from a rat medullary thyroid carcinoma. Goodman, R.H., Jacobs, J.W., Dee, P.C., Habener, J.F. J. Biol. Chem. (1982)
- A quantitative study of the coexistence of peptides in varicosities within the superficial laminae of the dorsal horn of the rat spinal cord. Tuchscherer, M.M., Seybold, V.S. J. Neurosci. (1989)
- Regulation of rat pancreatic CCKB receptor and somatostatin expression by insulin. Julien, S., Laine, J., Morisset, J. Diabetes (2004)
- A novel variant of ionotropic glutamate receptor regulates somatostatin secretion from delta-cells of islets of Langerhans. Muroyama, A., Uehara, S., Yatsushiro, S., Echigo, N., Morimoto, R., Morita, M., Hayashi, M., Yamamoto, A., Koh, D.S., Moriyama, Y. Diabetes (2004)
- Histamine secretion from rat enterochromaffinlike cells. Prinz, C., Kajimura, M., Scott, D.R., Mercier, F., Helander, H.F., Sachs, G. Gastroenterology (1993)
- Somatostatin inhibition of basal and carbachol-stimulated gastrin release in rat antral organ culture. Harty, R.F., Maico, D.G., McGuigan, J.E. Gastroenterology (1981)
- Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro. Billestrup, N., Swanson, L.W., Vale, W. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Growth hormone-releasing factor increases somatostatin release and mRNA levels in the rat periventricular nucleus via nitric oxide by activation of guanylate cyclase. Aguila, M.C. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Fractional reduction of somatostatin concentration interacted with rat growth hormone releasing hormone to titrate the magnitude of pulsatile growth hormone and prolactin release in perifusion. Stachura, M.E., Tyler, J.M., Farmer, P.K. Neuroendocrinology (1988)
- Somatostatin receptors mediating inhibition of basal and stimulated electrogenic ion transport in rat isolated distal colonic mucosa. McKeen, E.S., Feniuk, W., Humphrey, P.P. Naunyn Schmiedebergs Arch. Pharmacol. (1995)
- Analogues of somatostatin bind selectively to brain somatostatin receptor subtypes. Raynor, K., Coy, D.C., Reisine, T. J. Neurochem. (1992)
- The effect of pentagastrin on the somatostatin receptor/effector system in rat pancreatic acinar membranes. Alvaro-Alonso, I., Muñoz-Acedo, G., Arilla, E. Regul. Pept. (1994)
- Identification and characterization of endothelin receptor subtype B in rat retina. de Juan, J.A., Moya, F.J., Garcia de Lacoba, M., Fernandez-Cruz, A., Fernandez-Durango, R. J. Neurochem. (1993)
- Immunohistochemical colocalization of type II angiotensin receptors with somatostatin in rat pancreas. Wong, P.F., Lee, S.S., Cheung, W.T. Regul. Pept. (2004)
- Effect of diabetes in the BB Wistar rat on the peptidergic component of the enteric innervation. Buchan, A.M. Digestion (1990)
- Somatostatin co-localizes with tyrosine hydroxylase in the nerve cells of discrete hypothalamic regions in rats. Sakanaka, M., Magari, S., Inoue, N. Brain Res. (1990)
- Growth hormone-releasing factor-sensitive adenylate cyclase system of purified somatotrophs: effects of guanine nucleotides, somatostatin, calcium, and magnesium. Narayanan, N., Lussier, B., French, M., Moor, B., Kraicer, J. Endocrinology (1989)
- Somatostatin inhibits interleukin 6 release from rat cortical type I astrocytes via the inhibition of adenylyl cyclase. Grimaldi, M., Florio, T., Schettini, G. Biochem. Biophys. Res. Commun. (1997)
- Mechanisms of multiple organ damages in acute necrotizing pancreatitis. Zhang, Q., Ni, Q., Cai, D., Zhang, Y., Zhang, N., Hou, L. Chin. Med. J. (2001)
- Growth hormone-releasing factor and fibroblast growth factor regulate somatostatin gene expression. Zeytin, F.N., Rusk, S.F., De Lellis, R. Endocrinology (1988)
- Somatostatin and the somatostatin receptor 2 are reciprocally controlled by calcineurin during cerebellar granule cell maturation. Kramer, D., Caruso, A., Nicoletti, F., Genazzani, A.A. J. Neurochem. (2005)
- Endotoxin-induced release of interleukin-6 from rat medial basal hypothalami. Spangelo, B.L., Judd, A.M., MacLeod, R.M., Goodman, D.W., Isakson, P.C. Endocrinology (1990)
- Evidence for corticotropin-releasing factor, neurotensin, and somatostatin in the neural pathway from the central nucleus of the amygdala to the parabrachial nucleus. Moga, M.M., Gray, T.S. J. Comp. Neurol. (1985)
- Sucrose octasulfate stimulates gastric somatostatin release. Lucey, M.R., Park, J., DelValle, J., Wang, L.D., Yamada, T. Am. J. Med. (1991)