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Chemical Compound Review

Cyclophellitol     (1R,2R,3R,4S,5R,6S)-2- (hydroxymethyl)-7...

Synonyms: Cylcophellitol, Epi-cpl, CHEMBL35576, AG-K-76798, KST-1A1535, ...
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Disease relevance of Cyclophellitol


High impact information on Cyclophellitol


  1. Inhibition of experimental metastasis by an alpha-glucosidase inhibitor, 1,6-epi-cyclophellitol. Atsumi, S., Nosaka, C., Ochi, Y., Iinuma, H., Umezawa, K. Cancer Res. (1993) [Pubmed]
  2. Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice. Atsumi, S., Nosaka, C., Iinuma, H., Umezawa, K. Arch. Biochem. Biophys. (1992) [Pubmed]
  3. Cyclophellitol: a naturally occurring mechanism-based inactivator of beta-glucosidases. Withers, S.G., Umezawa, K. Biochem. Biophys. Res. Commun. (1991) [Pubmed]
  4. Biological activities of cyclophellitol. Atsumi, S., Iinuma, H., Nosaka, C., Umezawa, K. J. Antibiot. (1990) [Pubmed]
  5. Structural basis for cyclophellitol inhibition of a beta-glucosidase. Gloster, T.M., Madsen, R., Davies, G.J. Org. Biomol. Chem. (2007) [Pubmed]
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