Disease relevance of carbon monoxide

• Flue gas samples from eight different sources (industrial plants and crematories) have been analyzed for PCDD/Fs and PCBs and total Toxicity EQuivalents (TEQ) values have been calculated using the latest WHO toxicity equivalent factors from 1998 [1].

High impact information on carbon monoxide

• Binding of carbon monooxide results in the displacement of a thiolate ligand to the ferrous heme, and is accompanied by complete loss of cystathionine beta-synthase activity [2].
• Eight different forms of cytochrome P-450 have been isolated from the liver microsomes of male Sprague-Dawley rats and compared with previously characterized forms on the basis of chromatographic behavior, absorption maximum of the carbon monooxide complex, apparent molecular weight upon SDS-disc gel electrophoresis, and substrate specificity [3].
• Flue gas samples for PM2.5, PM coarse (PM2.5-10), and TSP were collected isokinetically using a cascade impactor; PM mass concentrations were determined gravimetrically [4].
• Flue gas desulfurization by means of SO2 absorption in seawater is a well-known process [5].
• As biosynthesis of leukotoxin was sensitive to carbon monooxide, it was concluded that cytochrome P-450 dependent monooxygenase is responsible for the biosynthesis [6].

Biological context of carbon monoxide

• Flue gas desulfurization residue did not affect germination and all application rates stimulated aboveground biomass [7].
• The hydroxylation activity was strongly inhibited by carbon monooxide and sulfhydryl reagents [8].
• Flue gas treatability studies: a tool for techno-economic control of industrial air pollution [9].
• The 15O-labelled carbon monooxide (C15O) single-breath inhalation method was used [10].
• Flue gas recirculation in the incinerator combustion chamber is an operative technique that offers substantial benefits in managing waste incineration [11].

Anatomical context of carbon monoxide

• Exhaust gas exposure induced aggregation and electron translucence of plastoglobuli, swelling of thylakoids, increase of cytoplasmic lipids and slight increase of vesiculation of cytoplasm in mesophyll cells of current and previous year needles [12].

Associations of carbon monoxide with other chemical compounds

• The kinetic data, the apparent Ki's for the four inhibitors and Km's for the substrate estradiol in the assays, along with the inhibition results with carbon monooxide suggest that different forms of cytochrome P-450 may be involved in the two hydroxylations [13].

Analytical, diagnostic and therapeutic context of carbon monoxide

• Exhaust gas samples collected at the outlet of the incinerator were analyzed for dioxins (PCDDs, PCDFs, and coplanar PCBs) by gas chromatography/mass spectrometry [14].

References