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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Incineration

  • Dioxin, a ubiquitous contaminant of industrial combustion processes including medical waste incineration, has been implicated in the etiology of endometriosis in animals [1].

High impact information on Incineration

  • The remaining CO arises in the coma, probably through thermal destruction of more complex molecules [2].
  • During the past decade it has been shown conclusively that the incineration of municipal and industrial wastes gives rise to emissions of chlorinated dibenzodioxins and dibenzofurans [3].
  • Model studies of polychlorinated dibenzo-p-dioxin formation during municipal refuse incineration [4].
  • After incineration hypercalcemic visceral deposits having an amorphous diffraction pattern were found to generate pyrophosphate supporting the presence of brushite in these deposits [5].
  • A literature survey and data from pilot-scale combustion experiments allow conclusions to be drawn on the relations between ClPhs and PCDD/Fs in municipal waste incineration and other combustion processes [6].

Biological context of Incineration

  • These results suggest that the bleaching and incineration of textile products containing Irgasan DP300 result in environmental pollution by PCDDs [7].
  • Spray dryer is the most prevailing air pollution control devise for removing acid gas in waste incineration; however, the performance of spray dryer on the removal of CO2 is seldom studied [8].
  • Disposal of the residual tissues and mercury by incineration would release the volatile elemental mercury into the atmosphere, where it would subsequently be returned to earth in rain water, be converted to methyl mercury by microorganisms, and enter the food chain [9].
  • DNA damage in mononuclear and polynuclear lymphocytes, and the level of the urinary metabolites, 1-OHP and 2-naphthol, were evaluated in both waste incineration workers and control subjects [10].
  • Inhalation of particles contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) will be an increasingly important route of human exposure in light of the increased utilization of municipal waste incineration and the resultant emission of contaminated materials into the environment [11].

Anatomical context of Incineration

  • However, T-cell activation was found to be significantly higher in the waste incineration workers than in the control subjects (p=0.001), although B-cell activation did not exhibit this trend [10].
  • 7-Ethylresorufin O-deethylase (EROD) activity and the cytochrome P-450 content of liver and kidney microsomes were measured in male and female nase (Chondrostoma nasus) from the River Rhône (France) caught downstream and upstream of a PCB incineration plant [12].
  • There was successful identification of human biological sex, from deciduous teeth exposed to incineration temperatures of 200 degrees C and below, using standard ethidium bromide gel staining [13].

Associations of Incineration with chemical compounds

  • Thermal destruction processes in proteins involving cystine residues [14].
  • The results are interpreted as indicating thermal destruction of nucleosomal structure in nuclear chromatin; dissociation of DNA from core histones results in its increasing ability to intercalate AO, most likely due to increased topological freedom to undergo unwinding and elongation following binding of the intercalator [15].
  • Dioxin danger from garbage incineration [16].
  • As part of an epidemiologic study on exposure to a toxic waste incineration plant we investigated whether blood concentrations of polychlorinated biphenyls (PCBs), lead, and cadmium, as well as concentration of mercury in 24-hr urine samples were associated with thyroid hormone status [17].
  • In the study area, pentachlorophenol and pentachlorophenol incineration sources have been identified, and the animal contamination and blood elevations probably reflect these sources [18].

Gene context of Incineration

  • 2,3,7,8-Tetrachlorobenzo-p-dioxin (TCDD), a halogenated compound that binds the aryl hydrocarbon receptor, is a by-product of numerous industrial processes including waste incineration [19].
  • In reviewing the congener profiles of industrial PCB products and emission gas, the following general trends were observed: (i) For congeners whose contents are high in industrial PCB products (e.g., 105 and 118), the amounts deposited were much higher than the amounts released with waste incineration emission gas [20].
  • This study illustrates a potential method for reducing PAH emissions from the incineration of biological sludge by adding a suitable and available waste as a co-fuel [21].
  • Rates of particle emissions from Manhattan incinerators estimated here correlate stronglywith Pb accumulation rates as a function of depth (time) in Central Park Lake sediments, consistent with refuse incineration emitting large amounts of atmospheric lead in NYC for many decades afterthe 1920s [22].
  • The mean values of 1-hydroxypyrene (1-OHP) in automobile emission inspection and waste incineration workers were 0.27+/-0.19 and 0.57+/-0.46 micromol/mol creatinine, respectively, and the mean values of 2-naphthol in automobile emission inspectors and waste incineration workers were 4.80+/-4.01 and 8.30+/-4.79 mol/mol creatinine, respectively [23].


  1. Serum dioxin concentrations and endometriosis: a cohort study in Seveso, Italy. Eskenazi, B., Mocarelli, P., Warner, M., Samuels, S., Vercellini, P., Olive, D., Needham, L.L., Patterson, D.G., Brambilla, P., Gavoni, N., Casalini, S., Panazza, S., Turner, W., Gerthoux, P.M. Environ. Health Perspect. (2002) [Pubmed]
  2. Identification of two sources of carbon monoxide in comet Hale-Bopp. DiSanti, M.A., Mumma, M.J., Dello Russo, N., Magee-Sauer, K., Novak, R., Rettig, T.W. Nature (1999) [Pubmed]
  3. Phenol and HCl at 550 degrees C yield a large variety of chlorinated toxic compounds. Eklund, G., Pedersen, J.R., Strömberg, B. Nature (1986) [Pubmed]
  4. Model studies of polychlorinated dibenzo-p-dioxin formation during municipal refuse incineration. Karasek, F.W., Dickson, L.C. Science (1987) [Pubmed]
  5. Extraosseous calcification. Evidence for abnormal pyrophosphate metabolism in uremia. Alfrey, A.C., Solomons, C.C., Ciricillo, J., Miller, N.L. J. Clin. Invest. (1976) [Pubmed]
  6. Perspectives on the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans during municipal solid waste (MSW) incineration and other combustion processes. Tuppurainen, K., Asikainen, A., Ruokojärvi, P., Ruuskanen, J. Acc. Chem. Res. (2003) [Pubmed]
  7. Formation of polychlorinated dibenzo-p-dioxins upon combustion of commercial textile products containing 2,4,4'-trichloro-2'-hydroxydiphenyl ether (Irgasan DP300). Kanetoshi, A., Ogawa, H., Katsura, E., Kaneshima, H., Miura, T. J. Chromatogr. (1988) [Pubmed]
  8. Removal of carbon dioxide by a spray dryer. Chen, J.C., Fang, G.C., Tang, J.T., Liu, L.P. Chemosphere (2005) [Pubmed]
  9. Case report: subcutaneous elemental mercury injection--clinical observations and implications for tissue disposal from the histopathology laboratory. Vernon, S.E. Ann. Clin. Lab. Sci. (2005) [Pubmed]
  10. Evaluation of immuno- and reproductive toxicities and association between immunotoxicological and genotoxicological parameters in waste incineration workers. Oh, E., Lee, E., Im, H., Kang, H.S., Jung, W.W., Won, N.H., Kim, E.M., Sul, D. Toxicology (2005) [Pubmed]
  11. Hepatic aryl hydrocarbon hydroxylase and cytochrome P450 induction following the transpulmonary absorption of TCDD from intratracheally instilled particles. Nessel, C.S., Amoruso, M.A., Umbreit, T.H., Gallo, M.A. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1990) [Pubmed]
  12. Use of the fish cytochrome P-450-dependent 7-ethylresorufin O-deethylase activity as a biochemical indicator of water pollution. Study of the liver and the kidney of male and female nase (Chondrostoma nasus) from the River Rhône. Masfaraud, J.F., Monod, G., Devaux, A. Sci. Total Environ. (1990) [Pubmed]
  13. Sex determination by PCR analysis of DNA extracted from incinerated, deciduous teeth. Williams, D., Lewis, M., Franzen, T., Lissett, V., Adams, C., Whittaker, D., Tysoe, C., Butler, R. Sci. Justice (2004) [Pubmed]
  14. Thermal destruction processes in proteins involving cystine residues. Volkin, D.B., Klibanov, A.M. J. Biol. Chem. (1987) [Pubmed]
  15. Thermal stability of nucleosomes studied in situ by flow cytometry: effect of ionic strength and n-butyrate. Darzynkiewicz, Z., Carter, S.P. Exp. Cell Res. (1989) [Pubmed]
  16. Dioxin danger from garbage incineration. Karasek, F.W., Hutzinger, O. Anal. Chem. (1986) [Pubmed]
  17. Exposure to polychlorinated biphenyls and levels of thyroid hormones in children. Osius, N., Karmaus, W., Kruse, H., Witten, J. Environ. Health Perspect. (1999) [Pubmed]
  18. Serum polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans among people eating contaminated home-produced eggs and beef. Goldman, L.R., Harnly, M., Flattery, J., Patterson, D.G., Needham, L.L. Environ. Health Perspect. (2000) [Pubmed]
  19. Serum dioxin concentrations and age at menopause. Eskenazi, B., Warner, M., Marks, A.R., Samuels, S., Gerthoux, P.M., Vercellini, P., Olive, D.L., Needham, L., Patterson, D., Mocarelli, P. Environ. Health Perspect. (2005) [Pubmed]
  20. Dioxin-like PCBs released from waste incineration and their deposition flux. Akai, S., Hayakawa, K., Takatsuki, H., Kawakami, I. Environ. Sci. Technol. (2001) [Pubmed]
  21. Potential method for reducing emissions of polycyclic aromatic hydrocarbons from the incineration of biological sludge for the terephthalic acid manufacturing industry. Wang, L.C., Lee, W.J., Tsai, P.J., Chen, S.J. Environ. Sci. Technol. (2002) [Pubmed]
  22. Refuse incinerator particulate emissions and combustion residues for New York City during the 20th century. Walsh, D.C., Chillrud, S.N., Simpson, H.J., Bopp, R.F. Environ. Sci. Technol. (2001) [Pubmed]
  23. DNA damage in T- and B-lymphocytes and granulocytes in emission inspection and incineration workers exposed to polycyclic aromatic hydrocarbons. Sul, D., Oh, E., Im, H., Yang, M., Kim, C.W., Lee, E. Mutat. Res. (2003) [Pubmed]
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