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Chemical Compound Review:

Azamplus bismuth;(E)-N-[2-[[5- (dimethylaminomethyl...

Synonyms: Elicodil, Helirad, Pylorid, Pylorisan, Tritec, ...

Ottlecz, A. et al., Ren, Z. et al., Graham, D.Y. et al., Vondracek, T.G., Duggan, A. et al., et al.

Buzás, Jozan, Ren, Borody, Pang, Dunkley, Clancy, Xia, Chu, Wong, Wong,

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Disease relevance of Helirad

Efficacy of ranitidine bismuth citrate (RBC) dual and triple therapies for the eradication of Helicobacter pylori [1].

High impact information on Helirad

METHODS: In this study we measured and analysed the inhibitory effect of ranitidine bismuth citrate (RBC, Pylorid, Tritec) on the activity and kinetics of phospholipase A2 (PLA2) (E.C.3.1.1.4) of commercial cobra (Naja naja) venom and H. pylori (French press lysates) using L-alpha-dipalmitoyl-(2[1-14C]palmitoyl)-phosphatidylcholine as substrate [2].
An alternative non-macrolide, non-imidazole treatment regimen for curing Helicobacter pylori and duodenal ulcers: ranitidine bismuth citrate plus amoxicillin. The RBC H. pylori Study Group [3].
DATA SOURCES: A MEDLINE search of the English-language literature from 1992 to January 1997 was conducting using the key terms Tritec, ranitidine, and bismuth [4].

Analytical, diagnostic and therapeutic context of Helirad

CONCLUSION: These data demonstrate that the Helirad Alert enzyme-linked immunoassay could provide a reliable method for screening H. pylori infection in both western and Chinese populations [5].
CONCLUSION: PPI/RBC-based triple therapies achieved comparable results with the meta-analyses [6].

References

Efficacy of ranitidine bismuth citrate (RBC) dual and triple therapies for the eradication of Helicobacter pylori. Duggan, A., Williamson, R. Gut (1998) [Pubmed]
Effect of ranitidine bismuth citrate on the phospholipase A2 activity of Naja naja venom and Helicobacter pylori: a biochemical analysis. Ottlecz, A., Romero, J.J., Lichtenberger, L.M. Aliment. Pharmacol. Ther. (1999) [Pubmed]
An alternative non-macrolide, non-imidazole treatment regimen for curing Helicobacter pylori and duodenal ulcers: ranitidine bismuth citrate plus amoxicillin. The RBC H. pylori Study Group. Graham, D.Y., Breiter, J.R., Ciociola, A.A., Sykes, D.L., McSorley, D.J. Helicobacter (1998) [Pubmed]
Ranitidine bismuth citrate in the treatment of Helicobacter pylori infection and duodenal ulcer. Vondracek, T.G. The Annals of pharmacotherapy. (1998) [Pubmed]
Evaluation of anti-Helicobacter pylori IgG2 antibody for the diagnosis of Helicobacter pylori infection in western and Chinese populations. Ren, Z., Borody, T., Pang, G., Dunkley, M., Clancy, R., Xia, H.H., Chu, K.M., Wong, J., Wong, B.C. Aliment. Pharmacol. Ther. (2005) [Pubmed]
First-line eradication of H pylori infection in Europe: A meta-analysis based on congress abstracts, 1997-2004. Buzas, G.M., Jozan, J. World J. Gastroenterol. (2006) [Pubmed]

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