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Chemical Compound Review

CHEMBL1105     2-(6-methoxynaphthalen-2- yl)ethanoic acid

Synonyms: SureCN253759, AG-A-06318, CHEBI:35628, ANW-47289, AK-80115, ...
 
 
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Disease relevance of BRL 10720

 

High impact information on BRL 10720

 

Anatomical context of BRL 10720

 

Gene context of BRL 10720

 

Analytical, diagnostic and therapeutic context of BRL 10720

References

  1. Liver insufficiency as a factor modifying the pharmacokinetic characteristic of the preparation nabumetone. Maleev, A., Vlahov, V., Gruev, I., Dierdorf, D., Kostova, N., Bacracheva, N. International journal of clinical pharmacology, therapy, and toxicology. (1986) [Pubmed]
  2. Photosensitizing properties of 6-methoxy-2-naphthylacetic acid, the major metabolite of the phototoxic non-steroidal anti-inflammatory and analgesic drug nabumetone. Canudas, N., Zamora, D., Villamizar, J.E., Fuentes, J., Castelli, C., Taddei, A. Die Pharmazie. (2005) [Pubmed]
  3. Polymorphonuclear leukocytes activation: in vitro modulation by 6-methoxy-2-naphthylacetic acid, the major active metabolite of nabumetone. Allegrezza-Giulietti, A., Serretti, R., Peroni, M., Cervini, C. Pharmacol. Res. (1993) [Pubmed]
  4. Preclinical overview of nabumetone. Pharmacology, bioavailability, metabolism, and toxicology. Mangan, F.R., Flack, J.D., Jackson, D. Am. J. Med. (1987) [Pubmed]
  5. Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA. Pillinger, M.H., Dinsell, V., Apsel, B., Tolani, S.N., Marjanovic, N., Chan, E.S., Gomez, P., Clancy, R., Chang, L.F., Abramson, S.B. Br. J. Pharmacol. (2004) [Pubmed]
  6. Simplex optimization of the variables affecting the micelle-stabilized room temperature phosphorescence of 6-methoxy-2-naphthylacetic acid and its kinetic determination in human urine. Pulgarín, J.A., Molina, A.A., Pardo, M.T. Anal. Biochem. (2005) [Pubmed]
  7. The in vitro effects of 6-methoxy-2-naphthylacetic acid, the active metabolite of nabumetone, on rat gastric mucosal eicosanoid synthesis and metabolism. Melarange, R., Spangler, R., Hoult, J.R. Prostaglandins Leukot. Essent. Fatty Acids (1996) [Pubmed]
  8. Effect of the antiinflammatory prodrug, nabumetone and its principal active metabolite on rat gastric mucosal, aortic and platelet eicosanoid synthesis, in vitro and ex vivo. Jeremy, J.Y., Thompson, C.S., Mikhailidis, D.P., Dandona, P. Prostaglandins Leukot. Essent. Fatty Acids (1990) [Pubmed]
  9. Extractionless determination of 6-methoxy-2-naphthylacetic acid, a major metabolite of nabumetone, in human plasma by high-performance liquid chromatography. de Jager, A.D., Hundt, H.K., Hundt, A.F., Swart, K.J., Knight, M., Roberts, J. J. Chromatogr. B Biomed. Sci. Appl. (2000) [Pubmed]
 
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