Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

Zitromax (2R,3S,4R,5R,8R,10R,11R,12R,13 S,14R)-11...

Synonyms: Trulimax, Azitrocin, Sumamed, Zentavion, Zithromax, ...

Rylander, M. et al., Wildfeuer, A. et al., Clement, A. et al., Wildfeuer, A. et al., Aronoff, S.C. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Zithromax

In vitro comparison of the activity of doxycycline, tetracycline, erythromycin and a new macrolide, CP 62993, against Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum [1].
Long term use of low dose azithromycin in young patients with cystic fibrosis has a beneficial effect on lung disease expression, even before infection with Pseudomonas aeruginosa [2].

High impact information on Zithromax

In-vitro activity of erythromycin, roxithromycin and CP 62993 against common paediatric pathogens [3].
In the concentration range examined (0.5-16 micrograms/ml) the azalide antibiotic azithromycin (CAS 83905-01-5, Zithromax) inhibited the growth of mycobacteria in macrophages over 7 days [4].

Anatomical context of Zithromax

Azithromycin (CAS 83905-01-5), a new azalide antibiotic, reached high concentrations in alveolar macrophages obtained from patients [5].

References

In vitro comparison of the activity of doxycycline, tetracycline, erythromycin and a new macrolide, CP 62993, against Mycoplasma pneumoniae, Mycoplasma hominis and Ureaplasma urealyticum. Rylander, M., Hallander, H.O. Scandinavian journal of infectious diseases. Supplementum. (1988) [Pubmed]
Long term effects of azithromycin in patients with cystic fibrosis: A double blind, placebo controlled trial. Clement, A., Tamalet, A., Leroux, E., Ravilly, S., Fauroux, B., Jais, J.P. Thorax (2006) [Pubmed]
In-vitro activity of erythromycin, roxithromycin and CP 62993 against common paediatric pathogens. Aronoff, S.C., Laurent, C., Jacobs, M.R. J. Antimicrob. Chemother. (1987) [Pubmed]
Intracellular activity of azithromycin against Mycobacterium avium complex in human macrophages. Wildfeuer, A., Haberreiter, A. Arzneimittel-Forschung. (1997) [Pubmed]
Uptake and subcellular distribution of azithromycin in human phagocytic cells. Demonstration of the antibiotic in neutrophil polymorphonuclear leucocytes and monocytes by autoradiography and electron microscopy. Wildfeuer, A., Reisert, I., Laufen, H. Arzneimittel-Forschung. (1993) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.